This paper focuses on the latest research and critical reviews on modern computing architectures, software and hardware accelerated algorithms for bioinformatics data analysis with an emphasis on one of the most important sequence analysis applications-hidden Markov models (HMM). We show the detailed performance comparison of sequence analysis tools on various computing platforms recently devel...

We introduce algorithms and architectures for automatic spike detection and alignment that are designed for low power. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel integral transform analysis and achieve 99% of the precision of a PCA detector, while requiring only 0.05% of the computational complexity. The algorithms execute autonomously, but req...

Based on the competition between members of a hierarchy of length scales in complex multi-scale systems, it is shown how clustering of active quantities into concentrated sets, like bubbles in a Swiss cheese, is a generic property that dominates the intermittent structure. The halo-like surfaces of these clusters have scaling exponents lower than that of their kernels, which can be as high as t...

Practice research networks may be one way of advancing knowledge translation and exchange (KTE) in psychotherapy. In this study, we document this process by first asking clinicians what they want from psychotherapy research. Eighty-two psychotherapists in 10 focus groups identified and discussed psychotherapy research topics relevant to their practices. An analysis of these discussions led to t...

Man-made slender structures are known to be sensitive to high levels of vibration due to their flexibility which often cause irreversible damage. In nature, trees repeatedly endure large amplitudes of motion, mostly caused by strong climatic events, yet with minor or no damage in most cases. A new damping mechanism inspired by the architecture of trees is identified here and characterized in th...

We present results from a new method for the solution of electromagnetic scattering from finite sets of twodimensional cylinders exhibiting sidewall deformations. Our model treats the sidewall deviation as a small perturbation on a circle; the response of a single cylinder to an arbitrary external field can then be calculated, and the interactions between the cylinders can be computed with a mu...

In the present study we explore material architectures that lead to enhanced dissipation properties by taking advantage of squirt-flow a local flow mechanism triggered by heterogeneities at the pore level. While squirt-flow is a known dominant source of dissipation and seismic attenuation in fluid saturated geological materials, we study its untapped potential to be incorporated in highly defor...

The ability of the site-frequency spectrum (SFS) to reflect the particularities of gene genealogies exhibiting multiple mergers of ancestral lines as opposed to those obtained in the presence of population growth is our focus. An excess of singletons is a well-known characteristic of both population growth and multiple mergers. Other aspects of the SFS, in particular, the weight of the right ta...

2014 The Lagrangian L03BC (r, 03B8) = 1/2(1 + 03BC)r2 + 1 2r203B82r(03BC cos 03B8) with 1 03BC ~ 3.1 is studied using a surface of section map. Regular and chaotic behaviour is exhibited. The numerical evidence suggests the motion is integrable for 03BC = 3. Integrability is proved by explicitly exhibiting a first integral. J. Physique 46 (1985) 1495-1500 SEPTEMBRE 1985, Classification Physics ...

To improve the effectiveness and QoS of service in a sensor network there are number of communication and localization architectures followed by sensor network. One of such architecture is clustering architecture. This architecture restrict the communication to short distances so that the energy consumption of a node is reduces. In this paper, the clustering architecture and functionality of Cl...