The avian retroviruses E26 and AMV carry mutated versions of the gene encoding the cellular transcription factor c-Myb. Surprisingly, these two mutant forms of Myb differ in the subsets of myeloid cells that they transform, the target genes that they activate, and the way in which they are regulated.

Dideoxynucleotide chain termination sequencing has been applied directly to genomic DNA templates by annealing radiolabeled oligodeoxynucleotide primers to unique sites in total yeast DNA and extending with avian myoblastosis virus (AMV) reverse transcriptase. The technique is used here to confirm the introduction of selectively altered tRNA genes into the Saccharomyces cerevisiae genome by gen...

Luminal isobutyrate, a relatively poor metabolized short-chain fatty acid (SCFA), induces HCO(3) secretion via a Cl-independent, DIDS-insensitive, carrier-mediated process as well as inhibiting both Cl-dependent and cAMP-induced HCO(3) secretion. The mechanism(s) responsible for these processes have not been well characterized. HCO(3) secretion was measured in isolated colonic mucosa mounted in...

Possible future changes of North Atlantic hurricane intensity and the attribution of past hurricane intensity changes in the historical period are investigated using phase 5 of the Climate Model Intercomparison Project (CMIP5), multimodel, multiensemble simulations. For this purpose, the potential intensity (PI), the theoretical upper limit of the tropical cyclone intensity given the large-scal...

In standard models of quantitative traits, genotypes are assumed to differ in mean but not variance of the trait. Here we consider directional selection for a quantitative trait for which genotypes also confer differences in variability, viewed either as differences in residual phenotypic variance when individual loci are concerned or as differences in environmental variability when the whole g...

Abstract Sea surface temperature (SST) changes in the Mediterranean have profound impacts on both regions and remote areas. Previous studies show that SST has significant decadal variability is comparable with Atlantic multidecadal (AMV). However, few discussed characteristics sources of predictability based observations. Here for first time we use observational datasets to reveal contributed b...

Non-intrusive technologies for the in-situ measurement of river morphological features are increasingly popular in scientific and practice communities due to their efficient productive data acquisition. While suspended load with optical acoustic is currently an active area research, bedform dynamics has not experienced similar progress. We have successfully demonstrated through laboratory exper...

The impact of observations in a data assimilation (DA) may depend on various factors, and one aspect that can affect the is specification background error covariance matrix. present study compares INSAT-3D atmospheric motion vector (AMV) traditional three-dimensional variational (3DVAR) DA system hybrid ensemble transform Kalman filter (ETKF)-3DVAR (HYBRID) available Weather Research Forecast (...