Calcium mobilization can regulate a wide range of essential functions of respiratory epithelium, including ion transport, ciliary beat frequency, and secretion of mucus, all of which are modified in cystic fibrosis (CF). SERCA2, an important controller of calcium signaling, is deficient in CF epithelium. We conducted this study to determine whether SERCA2 deficiency can modulate airway epitheli...

Background: Many studies have shown that CFRD has a negative impact on CF prognosis. Current guidelines advise to screen for CFRD with an OGTT yearly from the age of 10 12. In our center we do not routinely screen for CFRD because the OGTT is cumbersome and not an ideal screening test. We therefore want to exclude unfavourable clinical evolution due to late diagnosis. Methods: 23 CF patients wi...

Figure 1. Diatoms in cytologic samples of Florida manatees (Trichechus manatus latirostris) in A, C, D, F, G, J–L, bottlenose dolphins (Tursiops truncatus) in B, E, I, and a seahorse (Hippocampus erectus) in H. Wright–Giemsa stain.9100 objective (except F;920). (A) naviculoid benthic diatom; skin contamination of urine sediment; wet mount. (B) Nitzschia sp.; gastric fluid direct smear. (C) Navi...

Surfaces consisting of sub micron holes (0.420-0.765 μm) engineered into nanoparticle (12 nm) coatings were examined for marine antifouling behaviour that defines early stage settlement. Immersed surfaces were found to be resistant to a 5-hour attachment assay of Amphora coffeaeformis, a marine organism commonly found in abundance on fouled substrates such as foul-releasing paints and self-poli...

ozone modification method and air-oxidation were used for the surface treatment of polyacrylonitrile(pan)-based carbon fiber. the surface characteristics of carbon fibers were characterized by x-ray photoelectron spectroscopy (xps). the interfacial properties of carbon fiber reinforced polyamide 6 (cf/pa6) composites were investigated by means of the single fiber pull-out tests. as a result, it...