Isolated congenital fetal hand malformation is a rare finding1. The prevalence of limb reduction deformities is about 3-8 per 20,000 births2. An isolated amputation of an extremity can be due to amniotic band syndrome, exposure to a teratogen or a vascular accident2. A comprehensive obstetric ultrasonographic assessment as well as genetic counselling are ideal when a fetal hand abnormality is d...

We used a combined cuboid/cuneiform osteotomy to treat residual adductus deformity in idiopathic and secondary club feet. The mean follow-up for 27 feet (22 idiopathic, four arthrogrypotic and one related to amniotic band syndrome) was 5.0 years (2.0 to 9.8). All healed uneventfully except for one early wound infection. No further surgery was required in the 22 idiopathic club feet but four of ...

OBJECTIVE Increased levels of cell-free fetal DNA (f-DNA) in the maternal circulation are a potential noninvasive marker for fetal Down syndrome. Our objectives were to (1) determine whether f-DNA could be quantified by using archived serum and amniotic fluid, (2) examine whether serum f-DNA levels are elevated in Down syndrome pregnancies in a case-control series matched for gestational age an...

INTRODUCTION The incidence of facial cleft is rare and ranges between 1.43 and 4.85 per 100,000 births. To date, there have been few reports of detailed ophthalmologic examinations performed in cases of facial cleft. Here, we report a case of optic-nerve hypoplasia and anterior segment abnormality associated with facial cleft. CASE REPORT A 9-day-old female infant was delivered by cesarian se...

the past decade has witnessed the revival of amniotic membrane transplantation (amt) in ophthalmology. the importance of amt is due to its ability to reduce scarring and inflammation and to enhance wound healing and epithelialization, and also its anti-microbial properties. amniotic membrane has recently been used as a substrate for culturing limbal stem cells for transplantation. it has been u...

Amniotic fluid embolism is a rare obstetric complication. The exact pathogenesis of this syndrome remains unknown and significant controversy exists whether coagulopathy should always be present. We used thromboelastography to assess the effect of amniotic fluid on coagulation and platelet function in pregnant women. Different volumes of amniotic fluid (10-60 microl) were added to blood (330 mi...

OGAWA, Y. Fetal Pulmonary Surfactant in Amniotic Fluid of Ewes. Tohoku J. exp. Med., 1972, 108 (4), 307-315-The phospholipids in the amniotic fluid from healthy pregnant ewes at various stages of gestation were analyzed in relation to the fetal pulmonary surfactant. The most abundant phospholipid was phosphatidylcholine which increased as the term approached. Analysis on the positional specific...

We report two cases of band keratopathy who were treated with thick amniotic membrane that contained a basement membrane structure as a graft, after ethylenediaminetetraacetic acid chelation with trephination and blunt superficial lamellar keratectomy in the anterior stroma. In each case, basement membrane was destroyed and calcium plaque invaded into anterior stroma beneath Bowman's membrane. ...