To help individuals with Alzheimer’s disease live at home for longer, we are developing a mobile robotic platform, called ED, intended to be used as a personal caregiver to help with the performance of activities of daily living. In a series of experiments, we study speech-based interactions between each of 10 older adults with Alzheimers disease and ED as the former makes tea in a simulated ho...

Alzheimers disease is the most common form of dementia in adults aged 65 or older. Although many studies have measured the effect of tissue degeneration for subcortical structures such as the hippocampi, amygdala, and the ventricles, little is known about the changes that occur in the architecture of the white matter during the course of this disease. The shape and properties of white-matter st...

BACKGROUND Health care planning and research would benefit from tools that enable researchers to project the future burden of Alzheimer's disease (AD) and evaluate the effect of potential interventions. METHODS We created a web-based application of the AD prevalence model developed by Brookmeyer et al (Am J Public Health 1998;88:1337-42; Alzheimers Dement 2007;3:186-91). The user defines the ...

With the aging of baby boomers, numbers Americans living with or affected by dementia will rise dramatically. By 2025, an estimated 7.2 million are expected to have Alzheimer's disease, which is most common cause dementia, accounting for 60-80% cases. 1 2021 disease facts and figures. Alzheimers Dement. 2021; 17: 327-406 Crossref PubMed Scopus (744) Google Scholar In absence medical breakthroug...

Aging is the common denominator and the highest risk factor for macular degeneration and Alzheimers Disease (AD). Important pathological hallmarks common to both diseases are the presence of amyloid β (Aβ) in the senile plaques of the AD brain and in the drusen of age-related macular degeneration (AMD) patients, oxidative stress, and apoptotic cell death. Data suggest that a common pathogenic m...