It has been proposed that the antiestrogen tamoxifen induces liver tumors in rats and genotoxic effects in vitro through metabolic activation involving, initially, alpha-hydroxylation of the ethyl group. To test this hypothesis, the extent of DNA adduct formation in primary rat hepatocytes treated with tamoxifen and alpha-hydroxytamoxifen was investigated. Hepatocytes from female Fischer F-344 ...

In previous studies, two forms (alpha and beta) of the oestrogen receptor, with different immunological characteristics, were observed in the cytosol fraction of fetal guinea-pig uterus, by using a monoclonal antibody to the human oestrogen receptor (D547Sp gamma). Only the alpha form was recognized by the antibody, shifting its sedimentation coefficient in high-salt sucrose gradients. The pres...

L-Sorbose, an excellent cellulase and xylanase inducer from Trichoderma reesei PC-3-7, also induced alpha-L-arabinofuranosidase (alpha-AF) activity. An alpha-AF induced by L-sorbose was purified to homogeneity, and its molecular mass was revealed to be 35 kDa (AF35), which was not consistent with that of the previously reported alpha-AF. Another species, with a molecular mass of 53 kDa (AF53), ...

This study investigated the use of cotton linter fiber as a raw material for manufacturing carboxymethylated cellulose nanofiber (CM-CNF). Cotton mixed pulp (CLMP) and hardwood bleached kraft (HwBKP) were used preparing carboxymethlyated (CMC) based on degree carboxymethylation (CM) considering dosage sodium hydroxide: monochloroacetic acid: low high CMs. After CM reactions, we evaluated length...

The current study was conducted to identify the most important variables in activation phase of cellulose acetate production. Dry alpha pulp as raw material supplied by a local company with intrinsic properties viscosity equal 926 mL/g and water content 96%. In this regard, variables, including reaction time (T30, T60, T90 min), addition level acetic acid (C25, C35, C45 units per 100 dry cellul...

Polyanionic cellulose polymer is used as an additive in drilling mud in order to decrease water loss and mudcake- thickness. In this study effect of bulk and nanosize polyanionic cellulose on water loss and mud-cakethickness in mud drilling is investigated. Polyanionic cellulose nanoparticles are made by using of ball milling. Size of nanoparticles is measured by Particle size analyzer. Polyani...

We studied the usefulness of woodand cellulose-based diets for L. africanus Lesne. Three diets were prepared which differed on the base ingredients; wood particles (Diet 1), cellulose powder (Diet 2), and alpha-cellulose (Diet 3). The diets were provided to adult L. africanus and the number of larvae, as well as the number of adults that emerged sex ratio, and body weight of the progeny was det...

Bacterial cellulose is a biological polymer with a variety of extraordinary properties which make it a functional material for different industrial fields. This work aimed at monitoring the effects of three different organic acids and nanoparticles on the production, water holding capacity and structural characteristics of bacterial cellulose. Different concentrations of organic acids and nanop...