نتایج جستجو برای: allowable amplification factor

تعداد نتایج: 899771  

Journal: :Cancer research 1992
E M Berns J G Klijn W L van Putten I L van Staveren H Portengen J A Foekens

Amplification of the c-myc and HER2/neu genes was found in 20 and 23%, respectively, of primary breast cancer tissues derived from 282 patients (median follow-up, 74 months). c-myc amplification was observed more frequently in larger tumors (P = 0.01) and in lymph node-positive patients (P = 0.01) but was not associated with age, menopausal status, or with differentiation grade or steroid recep...

1991
Patrick Guillaume Johan Schoukens Rik Pintelon

Low crest-factor of excitation and response signals is desirable in transfer function measurements, since this allows the maximization of the signal-to-noise ratios (SNR’s) for given allowable amplitude ranges of the signals. The paper presents a new crest-factor minimization algorithm for periodic signals with prescribed power spectrum. The algorithm is based on approximation of the nondiffere...

Journal: :Journal of Japan Association for Earthquake Engineering 2007

  A new computational technique is presented to find the optimal base position of dual arm robots in order to carry maximum allowable load. The maximum allowable load on a desired trajectory is limited by the number of factors such as; actuators torque limits, kinematic constraints, and kinematic redundancy of cooperative manipulators. For a dual arm robot mounted on a rail or table, load works...

Journal: :BioTechniques 1997
Q Liu E C Thorland S S Sommer

A T-->C point mutation is shown to specifically inhibit PCR amplification when compared to wild-type controls in exon H of the factor IX gene. Multiple primers of different lengths and locations were designed to examine this phenomenon. The experiments suggest that poor annealing and/or extension from the downstream primer are responsible for the observed inhibition and that the mutation can ex...

2016
Alistair Hind Qiong Zhang Gudrun Brattström

In climate change science the term 'Arctic amplification' has become synonymous with an estimation of the ratio of a change in Arctic temperatures compared with a broader reference change under the same period, usually in global temperatures. Here, it is shown that this definition of Arctic amplification comes with a suite of difficulties related to the statistical properties of the ratio estim...

2015
Luca Magnani Darren K. Patten Van T.M. Nguyen Sung-Pil Hong Jennifer H. Steel Naina Patel Ylenia Lombardo Monica Faronato Ana R. Gomes Laura Woodley Karen Page David Guttery Lindsay Primrose Daniel Fernandez Garcia Jacqui Shaw Patrizia Viola Andrew Green Christopher Nolan Ian O. Ellis Emad A. Rakha Sami Shousha Eric W.-F. Lam Balázs Győrffy Mathieu Lupien R. Charles Coombes

Over 30% of ERα breast cancer patients develop relapses and progress to metastatic disease despite treatment with endocrine therapies. The pioneer factor PBX1 translates epigenetic cues and mediates estrogen induced ERα binding. Here we demonstrate that PBX1 plays a central role in regulating the ERα transcriptional response to epidermal growth factor (EGF) signaling. PBX1 regulates a subset of...

2016
Dohee Kwon Ji Yun Yun Bhumsuk Keam Young Tae Kim Yoon Kyung Jeon

AIM To investigate the clinicopathological features and prognostic implications of combined MYC and fibroblast growth factor receptor 1 (FGFR1) status in esophageal squamous cell carcinomas (ESCCs). METHODS All patients with ESCC (n = 180) underwent surgical resection at Seoul National University Hospital sometime between 2000 and 2013. A tissue microarray was constructed using cores obtained...

2011
Renee Bowen

I present a theory of optimal multilateral trade agreements with public political shocks. I show that “forbearance” where one country withholds retaliation when its trading partner receives a shock is a feature of an optimal agreement. This provides a rationale for countries not acting on retaliatory rights granted under GATT. I show that there is a limit to forbearance allowable in a self-enfo...

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