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OBJECTIVE To determine whether critically ill patients who receive allogenic packed red blood cell transfusions are at increased risk of developing nosocomial infections during hospitalization. DESIGN Retrospective database study utilizing Project IMPACT. SETTING A 40-bed medical-surgical-trauma intensive care unit in an 825-bed tertiary referral teaching hospital. PATIENTS One thousand s...

Blood transfusion has a well-documented clinical significance in several medical scenarios for instance severe anemia, massive blood loss caused by trauma, and major surgeries. Nevertheless, been associated with post-transfusion complications, such as mismatch reactions, transfusion-transmitted infections (TTIs).

background: the most appropriate route of tranexamic acid administration is controversial. in the current study, we compared the efficacy of intravenous (iv) and topical intra-articular tranexamic acid in reducing blood loss and transfusion rate in patients who underwent primary total knee arthroplasty. methods: one hundred twenty 120 patients were scheduled to undergo primary total knee arthro...

results a total of 6095 participants (36.4% male and 65.6% female) with the mean age of 92 (7-95) and mean ± sd of 34.6 ± 17.3 years were included in this study. fifteen persons (0.24%) were detected as hcv-positive and the highest prevalence was seen in age ≤ 12 years old (1%). a significant association was only detected between blood transfusion and hcv infection; therefore, those persons wit...

background: many of the multiple traumatized patients who refer to the hospital need transfusion. transfusion-related acute lung injury (trali) is a serious clinical syndrome associated with the transfusion of plasma-containing blood components. in the article, we present a case of trali following transfusion of packed red blood cells case presentation: a 24 year old male referred to shahid beh...

haemovigilance is a system with standard program to cover the entire transfusion chain, monitor, evaluate and analyse the data to improve patients’ safety. we report the implemented haemovigilance system in hospitals and transfusion reactions (tr) in iran. methods and materials: this was a prospective descriptive study. the national reporting system for transfusion incidents was introduced in j...

Highly presensitized patients wait longer for a renal allograft than unsensitized patients and have a poorer allograft survival rate. Repeated blood transfusions have been implicated in the induction and maintenance of sensitization. To determine the effect of recombinant human erythropoietin (rHuEPO) therapy on five transfusion dependent, highly sensitized adolescents on dialysis, we serially ...