نتایج جستجو برای: alkaptonuria

تعداد نتایج: 375  

Journal: :Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2012

Journal: :Japanese Journal of Cardiovascular Surgery 2019

2012
Marcella Laschi Laura Tinti Daniela Braconi Lia Millucci Lorenzo Ghezzi Loredana Amato Enrico Selvi Adriano Spreafico Giulia Bernardini Annalisa Santucci

Alkaptonuria (AKU) results from defective homogentisate1,2-dioxygenase (HGD), causing degenerative arthropathy. The deposition of ochronotic pigment in joints is so far attributed to homogentisic acid produced by the liver, circulating in the blood and accumulating locally. Human normal and AKU osteoarticular cells were tested for HGD gene expression by RT-PCR, mono- and 2D-Western blotting. HG...

2013
Jennifer C. Flanagan Jenna M. Lang Aaron E. Darling Jonathan A. Eisen David A. Coil

Here we present the draft genome of an actinobacterium, Curtobacterium flaccumfaciens strain UCD-AKU, isolated from a residential carpet. The genome assembly contains 3,692,614 bp in 130 contigs. This is the first member of the Curtobacterium genus to be sequenced.

Journal: :Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2013
Romaina Iqbal Lena Jafri Ali Haroon Aysha Habib Khan

This study was conducted to determine the association between place of residence (grouped into neighbourhoods), and 25-hydroxy D (25[OH]D) levels of individuals of Karachi. Addresses of 4788 individuals tested for 25[OH]D at the clinical laboratory of the Aga Khan University (AKU), Karachi, from January 2007 to June 2008 were reviewed. The neighbourhoods were categorized into ten, based on loca...

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