Non-alcoholic fatty liver disease is now recognized as the hepatic component of the metabolic syndrome. Non-alcoholic fatty liver disease is a spectrum of fat-associated liver conditions that can result in end-stage liver disease and the need for liver transplantation. Simple steatosis, or fatty liver, occurs early in non-alcoholic fatty liver disease and may progress to non-alcoholic steatohep...

BACKGROUND Alcoholic steatosis is the earliest and most common liver disease, and may precede the onset of more severe forms of liver injury. METHODS The effect of Korean Red Ginseng extract (RGE) was tested in two murine models of ethanol (EtOH)-feeding and EtOH-treated hepatocytes. RESULTS Blood biochemistry analysis demonstrated that RGE treatment improved liver function. Histopathology ...

curring in diabetes mellitus were investigated in contTast with those in fatty liyer in non-d{abetic, non-alcoholic diseases of the liver. An electron microscopic study of the liver with delayed ICG elimination reyealed thickening and amorphous growth of the sinusoidal wall with obscure pores followed by mernbraneous formation, narrowness of Disse' s space, rarefaction of sinusoidal microyilli ...

Liver biopsy, owing to its limitations and risks, is an imperfect gold standard for assessing the severity of the most frequent chronic liver diseases chronic hepatitis C (HCV), B (HBV) non alcoholic (NAFLD) and alcoholic (ALD) fatty liver diseases. This review summarizes the advantages and the limits of the available biomarkers of liver fibrosis. Among a total of 2,237 references, a total of 1...

BACKGROUND/AIMS Age, sex, gene and life style are modulating risks for colon cancer. Although alcohol intake may impact on colorectal adenoma, clear association has not been established yet. We aimed to investigate effects of alcohol consumption on the characteristics of colorectal adenoma. METHODS Patients who underwent colonoscopic polypectomy of colorectal adenoma in the department of gast...

ALCOHOLIC LIVER DISEASE HAS VARIOUS MANIFESTATIONS asymptomatic steatosis, alcoholic hepatitis and alcoholic cirrhosis, which substantially increase the risk for developing hepatocellular carcinoma. Transforming growth factor (TGF-β) signaling pathway is a major regulator in chronic liver diseases contributing to all liver disease progression from liver injury, inflammation and fibrosis to HCC....

AIMS/INTRODUCTION The present study aimed to explore the incidence of type 2 diabetes, and to develop a risk-scoring model for predicting diabetes among the adult health check-up population in East China. MATERIALS AND METHODS Participants from the Shanghai Baosteel Cohort (age ≥20 years) without diabetes at baseline were recruited in a 6-year follow-up study. In order to explore risk factors...

Unsafe use of alcohol results in approximately 2.5 million deaths worldwide, with cirrhosis contributing to 16.6% of reported deaths. Serum insulin levels are often elevated in alcoholism and may result in diabetes, which is why alcoholic liver disease and diabetes often are present together. Because there is a sizable population with these diseases alone or in combination, the purpose of this ...

In the last three decades the prevalence of non-alcoholic fatty liver disease has markedly increased. Results from epidemiologic studies indicate that not only a general overnutrition but rather a diet rich in sugar, fat and cholesterol (= Western style diet) maybe a risk factor for the development of non-alcoholic fatty liver disease. Concerning liver diseases, it is known that Deleted in mali...