A SYSTEMATIC THEORY of psychotherapy specific to the disease of alcoholism has

This letter to the editor raises the issue of baclofen and the French experience with ‘its potentially miraculous effects’ on alcohol dependence. Much of this stems from a French cardiologist, Olivier Ameisen, who suffered from alcohol dependence and tested baclofen on himself with great success. There was a study in the Lancet in 2007 which showed some promising results but there has been litt...

Interventions for a variety of emotional and behavioral problems are commonly delivered in the context of treatment groups, with many using rolling admission to sustain membership (i.e., admission, dropout, and discharge from group are perpetual and ongoing). The authors present an overview of the analytic challenges inherent in rolling group data and outline commonly used (but flawed) analytic...

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No association between acetylation phenotype and alcoholism was discovered. Fifty-four percent of both the alcoholic patients and healthy volunteers were rapid acetylators. Acetylation phenotyping is not helpful to the investigation of the genetics of alcoholism.

We tested whether children show greater internalizing symptoms when their parents are actively abusing alcohol. In an integrative data analysis, we combined observations over ages 2 through 17 from two longitudinal studies of children of alcoholic parents and matched controls recruited from the community. Using a mixed modeling approach, we tested whether children showed elevated mother- and ch...