conclusions the current study findings indicated that echinacea purpurea extract played an important role in the protection against den toxicity in rats. results den induced hepatotoxicity and nephrotoxicity in all the treated animals by elevated serum alt, ast, alp and bun, creatinin and total and direct bilirubin levels. ast, bun and total and direct bilirubin significantly decreased in den +...

INTRODUCTION This study was conducted to compare the genotype and markers of disease severity of chronic hepatitis C (CHC), namely viral load, alanine transaminase (ALT) levels and histopathological findings on liver biopsy, in patients with and without end-stage renal disease (ESRD). METHODS This was a cross-sectional retrospective comparative study that included ESRD patients on haemodialys...

objective: in traditional medicaments, teucrium polium is used as anti-fungal, antibacterial, anti-inflammatory and antidiabetic. modern researches have shown that use of t. polium in vitro leads to decrease in fatty acids. to confirm the anti-diabetic evidences of teucrium polium this survey was done to evaluate the effect of boiled aqueous extract of t. polium on serum lipids, body weight and...

BACKGROUND Current guidelines introduce periodic monitoring of serum alanine transaminase (ALT) as the first-line modality in follow-up patients, with a hepatitis B virus (HBV) inactive carrier state. OBJECTIVES This study aimed to determine the incidence rate and patterns of ALT fluctuations and prognostic values for the development of chronic HBV e antigen (HBeAg)-negative hepatitis B (CHB)...

Background: Antibiotics are increasingly being prescribed during pregnancy. Even though safe non-teratogenic drugs prescribed, due to altered pharmacokinetics pregnancy can have adverse effects on hepatic metabolism. Methods: This was a prospective analytical study conducted in the department of obstetrics and gynecology at ESIC Medical College PGIMSR, Bengaluru, Bengaluru from August 2022 Janu...

BACKGROUND Alanine transaminase (ALT) and aspartate aminotransferase (AST) are referred to as liver transaminases. Although used routinely in clinical practice for decades, their role as predictors of mortality has not been examined until recently. We studied the predictive value of these serum transaminases in patients with ST-segment elevation myocardial infarction (STEMI) treated with primar...

BACKGROUND AND AIMS Patients with chronic hepatitic C (HCV) infection and normal serum alanine transaminase (ALT) levels were considered to have mild disease. In Taiwan, these patients were not suggested for interferon (IFN) based therapies. The aim of study is to compare therapeutic outcomes between HCV patients with normal and elevated ALT levels. METHODS We conducted a retrospective study ...

background alanine aminotransferase (alt) level is the most common diagnostic test used for detection of liver damage; however in the past few years some studies have questioned the normal aminotransferase range in adults and have suggested its revision. objectives in this study, we assessed the upper limit of alt and aspartate transaminase (ast) in a healthy population of iranian children. pat...

background: the mechanism of cadmium induced osteoporosis is not well understood, so in this study, we examined the toxicity of bone marrow mesenchymal stem cell (mscs) following treatment of rats with cdcl2 in drinking water, to revile the effect of this chemical on differentiation potential of mscs. methods: at the end of third passage, mscs were grown in the osteogenic medium for 21 days. to...

background crimean-congo hemorrhagic fever (cchf) was a rare disease in iran before 1999. during the last 15 years, it has been reported from different provinces of iran, mostly from southeastern iran. objectives this study aimed to evaluate the factors associated with poor outcome in children and adolescents with cchf. patients and methods we studied all files of children (age < 19 years old) ...