In this work we present a flexible tool for tumor progression, which simulates the evolutionary dynamics of cancer. Tumor progression implements a multi-type branching process where the key parameters are the fitness landscape, the mutation rate, and the average time of cell division. The fitness of a cancer cell depends on the mutations it has accumulated. The input to our tool could be any fi...

This article studies the properties of a distributed mechanism to perform the Vickrey auction. This mechanism, which was originally presented in López, Núñez, Rodríguez, and Rubio (2004), has the main characteristic that most of the information concerning the bids is kept private for both bidders and the auctioneer without the necessity of any trusted third party. In particular, after the aucti...

INTRODUCTION: Cost-analysis research can influence healthcare policies and practice patterns. There are three major perspectives in cost analysis research: the third-party payer, the hospital, and societal. Cost-analysis research has inherent bias depending on the chosen cost perspective. Subsequent conclusions based on cost-analysis research can change based on the perspective used.1 These per...

Increasing efficiency in hospitals is of particular importance. Studies that combine data from multiple hospitals/data holders can tremendously improve the statistical outcome and aid in identifying efficiency markers. However, combining data from multiple sources for analysis poses privacy risks. A number of protocols have been proposed in the literature to address the privacy concerns; howeve...

Students entering into their first year of university studies are subject to a jarring difference between the learning experiences of high school and university. High schools typically take a very structured approach to teaching whereas university expects students to take ownership of their learning. This dramatic shift often means students are not adequately prepared to form positive study hab...

In an interference-between-cues design, the expression of a learned Cue A --> Outcome 1 association has been shown to be impaired if another cue, B, is separately paired with the same outcome in a second learning phase. In the present study, we assessed whether this interference effect is mediated by participants' previous causal knowledge. This was achieved by having participants learn in a di...

surgical removal of impacted third molars is amongst the most common surgical procedures performed by oral and maxillofacial surgeons. every year many articles are published in different journals regarding different aspects in such surgeries. it is necessary to translate such vast amounts of data into simple and easily comprehensible sentences for the students of dentistry and oral surgery. thi...

Continuing the work K. C. Das, I. Gutman, B. Furtula, On second geometric-arithmetic index of graphs, Iran. J. Math Chem., 1(2) (2010) 17-28, in this paper we present lower and upper bounds on the third geometric-arithmetic index GA3 and characterize the extremal graphs. Moreover, we give Nordhaus-Gaddum-type result for GA3.