Exposure to ozone in air pollution in urban environments is associated with increases in pulmonary-related hospitalizations and mortality. Because ozone also alters clearance of pulmonary bacterial pathogens, we hypothesized that inhalation of ozone modifies innate immunity in the lung. To address our hypothesis, we exposed C57BL/6J mice to either free air or ozone, and then subsequently challe...

Cytokine-induced neutrophil chemoattractant (CINC) is a rat chemokine with potent chemoattractant effects on neutrophils. We determined the involvement of CINC in ozone-induced airway neutrophilia and bronchial hyperresponsiveness (BHR) in the rat. We found a marked increase in lung CINC messenger RNA (mRNA) within 2 h after cessation of ozone exposure (1 ppm for 3 h), as measured by Northern b...

air pollution is a challenging issue in some of the large cities in developing countries. air quality monitoring and interpretation of data are two important factors for air quality management in urban areas. several methods exist to analyze air quality. among them, we applied the dynamic neural network (tdnn) and radial basis function (rbf) methods to predict the concentrations of ground-level...

BACKGROUND Ozone concentrations in ambient air are related to cardiopulmonary perturbations in the aging population. Increased central sympathetic nerve activity induced by local airway inflammation may be one possible mechanism. METHODOLOGY/PRINCIPAL FINDINGS To elucidate this issue further, we performed a randomized, double-blind, cross-over study, including 14 healthy subjects (3 females, ...

An operational model evaluation procedure is described to quantitatively assess the relative skill among several regionalscale air quality models simulating various percentiles of the cumulative frequency distribution of observed daily maximum 8-h ozone concentrations. Bootstrap sampling is used to characterize the variability in the observed percentile values, thereby providing a means for ass...

Air pollution is one of the most important environmental problems in urban areas, being extremely critical in Mexico City. The main air pollution problem that has been identified in Mexico City metropolitan area is the formation of photochemical smog, primarily ozone. The study and development of modeling methodologies that allow the capturing of time series behavior becomes an important task. ...

This paper investigates the efficiency of Support Vector Machines for ozone peak and air pollution forecasting. A specific methodology adapted to the data has been proposed. The method is based on regression estimation of the ozone concentration for a given day. Then for the classification problem (deciding whether that day is polluted or not), the regression value is stacked. Model selection p...

Air quality health impact assessment (HIA) synthesizes information about air pollution exposures, health effects, and population vulnerability for regulatory decision-making and public engagement. HIAs often use annual average county or regional data to estimate health outcome incidence rates that vary substantially by season and at the subcounty level. Using New York City as an example, we ass...