AGRO100 (also known as AS1411) is a G-rich oligonucleotide that has long been established as a potent anti-cancer aptamer. However, the structure of AGRO100 remained unresolved, due to the co-existence of multiple different G-quadruplex conformations. We identified a DNA sequence named AT11, derived from AGRO100, which formed a single major G-quadruplex conformation and exhibited a similar anti...

Ground-based monitoring of rangeland condition is common in Australian pastoral administration systems. In the Northern Territory, such monitoring is officially seen as a key plank of sustainable pastoral land use. In the NT and elsewhere, these monitoring schemes have sought to increase participation by pastoralists. Involvement of pastoralists in monitoring is theoretically an educative proce...

Recent estimates suggest that more than 10% of Southern Africa is HIV+. This article is based on a research study of sixty four pastoral care projects focussing on the HIV/AIDS pandemic in Southern Africa. The projects, which fall under the auspices of the Southern African Catholic Bishops' Conference AIDS office, focus on both education for HIV prevention and the pastoral care of people living...

Drought and famine in Sub-Saharan Africa is among the leading contributory causes of vulnerability in pastoral communities. This paper discusses approaches that allow understanding of pastoral indigenous adaptive strategies to drought and famine. It is argued that understanding pastoral livelihood strategies requires a holistic approach. The paper focused on three key approaches namely: sustain...

Feed resources availability at cheap and affordable prices for livestock consumption are major factors determining capability of livestock production to supply products for increasing urban and cities consumers in Nigeria. To take advantages of the high demand in urban areas, livestock producers on extensive pastoralism are moving closer to cities and urban communities such as Abuja the Nigeria...

Agriculture must find new ways to reduce costs and increase efficiency meet the rising demand for products, avoiding waste due potential food scarcity. Through systematic literature review methodology, this study analyzes synthesizes existing on lean manufacturing (LM) applied in agro-pastoral production, its impact reduction losses waste, productivity increases considering production function ...

BACKGROUND This study was carried out to investigate the status of brucellosis in cattle under various management systems in Adamawa, Kaduna and Kano states, northern Nigeria. Using multi-stage sampling, serum samples of 4,745 cattle from 271 herds were tested using the Rose-Bengal plate-agglutination test (RBPT) and positives were confirmed using a competitive enzyme-linked immunosorbent assay...