OBJECTIVE To assess the effect of exercise on water turnover in endurance trained middle aged men. METHODS Water turnover was assessed using 2H2O as a tracer for water in six exercising and six sedentary middle aged men over seven consecutive days. The exercising subjects ran on average 14.8 km per day, while the sedentary group did not take part in any regular physical activity. RESULTS Th...

BACKGROUND AND AIMS The aim of the present study was to examine whether deeper processing of words during encoding in middle-aged adults leads to a smaller increase in word-learning performance and a smaller decrease in retrieval effort than in young adults. It was also assessed whether high education attenuates age-related differences in performance. METHODS Accuracy of recall and recognitio...

Previous genetic studies have suggested a history of sub-Saharan African gene flow into some West Eurasian populations after the initial dispersal out of Africa that occurred at least 45,000 years ago. However, there has been no accurate characterization of the proportion of mixture, or of its date. We analyze genome-wide polymorphism data from about 40 West Eurasian groups to show that almost ...

The aim was to determine whether the effects of age, period (from 1987 to 1997), or cohort (birth-cohort) are the most plausible explanations for the variation in dentist utilisation over time in Spain. On the basis of three sequential Spanish National Health Surveys, the trend in the percentage of people visiting the dentist within the previous 3 months was analysed by means of a standard coho...

The aim of the study was to clarify the aging-associated changes in physical performance and energy metabolism in senescence-accelerated prone mouse (SAMP1). The endurance of aged SAMP1 was significantly lower by 28% than the age-matched senescence-resistant mouse (SAMR1). Oxygen consumption and fat oxidation in aged SAMP1 were lower by 19% and 22%, respectively. Peroxisome proliferator-activat...

Mouse lemurs are suggested to represent promising novel non-human primate models for aging research. However, standardized and cross-taxa cognitive testing methods are still lacking. Touchscreen-based testing procedures have proven high stimulus control and reliability in humans and rodents. The aim of this study was to adapt these procedures to mouse lemurs, thereby exploring the effect of age...

results out of the 129 elderly participants, aged between 60-87 years (mean: 66.71 ± 6.21), males constituted 58.1% (n = 75) of patients and female were 41.9% (n = 54). normal variations of oral mucosa were observed in 62% (n = 80) of patients, while 44.2% (n = 57) had oral mucosal lesions. normal variations were significantly associated with smoking (or = 1.2), while denture wearers were at hi...

OBJECTIVE To determine the factors contributing to the initiation and propagation of smoking in visitors to a major tertiary health center in Karachi, Pakistan. METHODS Seven major contributing factors to the initiation and propagation of smoking were presented to consenting study participants (n=170) in a questionnaire. Participants were then requested to use their experience and opinion to ...

Age-related changes in temporal order memory have been well documented in older adults; however, little is known about this ability during middle age. We tested healthy young, middle-aged, and older adults on a previously published visuospatial temporal order memory test involving high and low interference conditions. When interference was low, young and middle-aged adults did not differ, but b...