BACKGROUND Age-related macular degeneration (AMD) is the leading cause of visual impairment and blindness in the Western World in those aged 65 and older. At present, several treatment modalities are utilised and several more are undergoing investigation in an attempt to retard the occurrence and progression of this devastating condition. AIMS To provide the non-ophthalmologist with an unders...

As the medical community has accepted that age-related macular degeneration (AMD) is a disease influenced by genetics, so too has it uncovered patterns in patients’ genetic profiles that suggest some individuals are at increased risk for initiation or progression of the disease. However, genetics is not everything, and retina specialists need to remember that AMD is a complex disorder that is a...

The arrival of aflibercept adds a new player to the treatment strategy for exudative macular diseases. The VIEW study proved that bimonthly intravitreal aflibercept injections were non-inferior to monthly ranibizumab injections in patients with treatment-naïve neovascular age-related macular degeneration (ARMD).1 Various studies followed that paper analysing the role of aflibercept in cases of ...

BACKGROUND The role of light exposure in the development of age-related macular degeneration (ARMD) has been questioned. We present the relationship between lifetime light exposure and ARMD as examined in the Pathologies Oculaires Liées à l'Age (POLA) study. METHODS The POLA study is a population-based study on cataract and ARMD and their risk factors. It included 2584 residents of the town o...

BACKGROUND The wet form of age-related macular degeneration (ARMD) is a leading cause of irreversible blindness in Caucasians. Our purpose was to assess influence of gene polymorphisms A69S (rs10490924) and R38X (rs2736911) ARMS2 and Y402 (rs1061170) CFH on wet ARMD risk in a Polish population. MATERIAL/METHODS 130 unrelated patients (90 with wet ARMD and 40 controls) took part in the study. ...

Age-related macular degeneration (ARMD) is the leading cause of blindness in developed world but there are still much unknown facts about the disease itself. Age, genetic factors and smoking are the three main risk factors for the development of ARMD, but the exact pathophysiological mechanism of the disease remains unknown. Current high resolution optical coherence tomography devices provide a...

Dear Editor: We read with interest the article “Approach of Turkish ophthalmologists to micronutrition in age-related macular degeneration” by Şahın et al. They aimed to evaluate the knowledge and behavior of ophthalmologists in Turkey with regard to micronutrition support in patients with age-related macular degeneration (ARMD). We congratulate the authors on their well-designed study. We woul...

INTRODUCTION age-related macular degeneration (ARMD) is a leading cause of blindness in the elderly population. OBJECTIVE to frame a profile of patients withARMD and find out the factors associated with it MATERIALS AND METHODS a cross-sectional study was carried out including a total of 75 patients with ARMD presenting to the out-patient department of a tertiary level ophthalmic center in ...