Background: Metabolic syndromes have been identified as a major risk factor for people with cardiovascular disease. Metabolic syndromes are defined as a range of conditions including waist-fat, abdominal obesity, high blood pressure, diabetes, high triglycerides, and HDL. Considering the importance of controlling metabolic syndrome, the research study subject with the mentioned aim is so import...

Reactive carbonyl compounds are formed during autoxidation of carbohydrates and peroxidation of lipids. These compounds are intermediates in the formation of advanced glycation end products (AGE) and advanced lipoxidation end products (ALE) in tissue proteins during aging and in chronic disease. We studied the reaction of carbonyl compounds glyoxal (GO) and glycolaldehyde (GLA) with pyridoxamin...

Many different access control policies and models have been developed to suit a variety of goals; these include Role-Based Access Control, One-directional Information Flow, Chinese Wall, Clark-Wilson, N-person Control, and DAC, in addition to more informal ad hoc policies. While each of these policies has a particular area of strength, the notational differences between these policies are subst...

BACKGROUND Regularity effect can affect performance in prospective memory (PM), but little is known on the cognitive processes linked to this effect. Moreover, its impacts with regard to aging remain unknown. To our knowledge, this study is the first to examine regularity effect in PM in a lifespan perspective, with a sample of young, intermediate, and older adults. OBJECTIVE AND DESIGN Our s...

I study a model of dynamic policy making in which citizens do not have complete knowledge of how policies are mapped into outcomes. They learn about the mapping through repeated elections as policies are implemented and outcomes observed. I characterize for this environment the policy trajectory with impatient voters. I find that through experimentation good policies are frequently found. Howev...

The product of the KRAS oncogene, KRAS4B, promotes tumor growth when associated with the plasma membrane (PM). PM association is mediated, in part, by farnesylation of KRAS4B, but trafficking of nascent KRAS4B to the PM is incompletely understood. We performed a genome-wide screen to identify genes required for KRAS4B membrane association and identified a G protein-coupled receptor, GPR31. GPR3...

This paper presents a preventive maintenance (PM) policy for leased equipment over a finite lease period L. Maintenance is entrusted to the lessor. The purpose is to determine the PM period T minimizing the expected total cost over the lease period in a context where repairs and PM actions are imperfect and have non-negligible durations. The leased equipment is periodically subjected to imperfe...

Epidemiologic studies of the link between particulate matter (PM) concentrations and mortality rates have yielded a range of estimates, leading to disagreement about the magnitude of the relationship and the strength of the causal connection. Previous meta-analyses of this literature have provided pooled effect estimates, but have not addressed between-study variability that may be associated w...