Normal aging is associated with both structural changes in many brain regions and functional declines in several cognitive domains with advancing age. Advanced neuroimaging techniques enable explorative analyses of structural alterations that can be used as assessments of such age-related changes. Here we used voxel-based morphometry (VBM) to investigate regional and global brain volume differe...

None funding has been received for this work from NIH, Wellcome Trust, HHMI or others. The authors have non conflict of interests to report, and results of the present study do not constitute endorsement by ACSM. ABSTRACT Purpose: i) to investigate the effect of age on gender difference in Hawaii Ironman triathlon performance time, and ii) to compare the gender difference between swimming (3.8 ...

BACKGROUND: Research question: Is there any difference in the outcome between Adolescent pregnancy and pregnancy in the adult mothers i.e. 20 – 29 yrs. Aim: To compare the perinatal and maternal outcome of pregnancy between the adolescent and older primigravidae. MATERIALS AND METHODS: It was a Hospital-based comparison study. 100 adolescent primigravidae who delivered in the teaching hospital ...

The P1/P50 midlatency auditory evoked potential is a sleep state-dependent waveform present during waking and rapid eye movement (REM) sleep and absent during slow-wave sleep. The P50 potential was studied in normal male and female subjects of various ages including post-pubertal adolescents (12-19 yrs), young adults (24-39 yrs), middle-aged adults (40-55 yrs) and older adults (55-78 yrs). Ther...

BACKGROUND The incidence of community-associated methicillin-resistant Staphylococcus aureus (MRSA) has risen dramatically in the U.S., particularly among children. Although Streptococcus pneumoniae colonization has been inversely associated with S. aureus colonization in unvaccinated children, this and other risk factors for S. aureus carriage have not been assessed following widespread use of...

The phase 3 CLEAR study showed statistically significant PFS (primary endpoint) and OS benefits, improved ORR with LEN + PEMBRO vs SUN in pts aRCC the 1L setting. We report updated efficacy describe who completed 2 years of continued on monotherapy. Pts no prior systemic therapy were randomized (1:1:1) to receive 20 mg PO QD 200 IV Q3W; 18 EVE 5 QD; or 50 (4 weeks on/2 off). Randomization was s...

To examine the strength and direction of the relationship between physical activity level, screen use and BMI in a cohort at ages 6, 8, 10 and 14 yrs as part of a prospective longitudinal cohort study. The sample comprised 1403 males and females who participated in the follow-up survey at 14 yrs of age between 2003 and 2005. Exploratory structural equation modelling was used to examine the inte...

Community-acquired pneumonia (CAP) is now most frequent in elderly patients. CAP in the younger patient has attracted much less attention. Therefore, we compared patients with CAP aged 18 to <65 yrs with those aged ≥ 65 yrs. Data from the prospective multicentre Competence Network for Community Acquired Pneumonia Study Group (CAPNETZ) database were analysed for potential differences in baseline...

INTRODUCTION The prevalence of childhood and adolescent obesity is increasing, with negative medical and psychosocial consequences. AIMS This study examines the association between weight status and nutrient intake, sport and leisure habits of middle school students in Bologna (Italy). METHODS Anthropometric data (height, weight) of 598 subjects (321 males and 277 females) 11-14 years old w...