Recent studies of Chesapeake Bay hypoxia suggest higher susceptibility to hypoxia in years after the 1980s. We used two simple mechanistic models and Bayesian estimation of their parameters and prediction uncertainty to explore the nature of this regime shift. Model estimates show increasing nutrient conversion efficiency since the 1980s, with lower DO concentrations and large hypoxic volumes a...

OBJECTIVE To assess the impact of screening on the incidence of and mortality from cervical cancer. DESIGN Comparison of age specific incidence and mortality before and after the introduction of the national call and recall system in 1988. SETTING England. SUBJECTS Women aged over 19 years. RESULTS From the mid-1960s, the number of smears taken rose continuously to 4.5 million at the en...

Objective To assess the impact of screening on the incidence of and mortality from cervical cancer. Design Comparison of age specific incidence and mortality before and after the introduction of the national call and recall system in 1988. Setting England. Subjects Women aged over 19 years. Results From the mid-1960s, the number of smears taken rose continuously to 4.5 million at the end of the...