The chemotherapeutic agent 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC) is used in the treatment of malignant melanoma where response rates of 15 to 30% have been reported. Some current interest exists in combining DTIC chemotherapy with localized high-dose (800 rads)-per-fraction radiotherapy in the treatment of unresectable metastatic mel anoma. The present work investigates the ...

Magnesium Ferrite (MgFe2O4) spinel structures prepared by a solid-state reaction was used as an anode modifier in the microbial fuel cell (MFC) treatment of Congo red dye. The performance reactors with unmodified stainless-steel mesh (CR-1) and MgFe2O4 coated stainless steel (CR-2) were tested compared followed aerobic treatment. peak power density observed to be 295.936 430.336 mW/m2 revealing...

Background: Aerobic and intense exercises with an increase in free radicals cause damages at the cellular level, heart disease, cancer, development of aging processes, which one its symptoms is increased serum concentrations liver enzymes. Objective: The purpose this study was to investigate concurrent effect four weeks aerobic training propolis supplementation on activity enzymes, including AL...

Background Previous studies have indicated that exercise training improves body composition and cardiovascular disease risk factors. The aim of the present study was to investigate the effect of 12 weeks of aerobic, strength and combined training on body composition, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and C-reactive protein (CRP) in sedentary...

blood hypercoagulability or thrombogenicity can be one of the main causes of the cardiovascular diseases in young population without traditional pathologic risk factors such as diabetes mellitus, hypertension or hyperlipidemia. the effect of aerobic exercise on coagulation and fibrinolysis has been studied extensively regarding to the effectivness of resistance exercises to increase functional ...

The metabolism of SR 4233 (3-amino-1,2,4-bentotriazine-1,4-dioxide), recently reported as highly toxic to hypoxic cells in vitro, was studied by using suspensions of Chinese hamster ovary cells. The rates of formation of two known reduction products, the 1-oxide and the unoxygenated 3-aminobenzotriazine, were measured in aerobic and hypoxic cell suspensions for drug treatments producing both hy...

The beneficial effects of exercise have been recognized for many years yet the molecular mechanisms by which exercise show benefits on health are still elusive. A combination of experimental and bioinformatics approaches can be an invaluable tool to increase the cellular understanding of the molecular mechanisms that underlie the aerobic exercise in obese adolescents. Muscle skeletal proteins w...