A technological advance in shaped ?-PD crystal growth provided us with high-quality single crystalline fibres of rare-earth garnets the good longitudinal transparency and light attenuation length up to 1 m.

To determine the natural history and psychological impact of the growth pattern in boys with constitutional delay in growth and puberty (CDGP), 43 boys presenting with short stature due to CDGP were followed up to final height. At presentation mean (SD) chronological age was 14.0 (1.9) years, bone age delay 2.7 (1.0) years, standing height standard deviation score (SDS) -3.4 (0.6), and predicte...

Dynamic microtubules (MTs) are required for neuronal guidance, in which axons extend directionally toward their target tissues. We found that depletion of the MT-binding protein Xenopus cytoplasmic linker-associated protein 1 (XCLASP1) or treatment with the MT drug Taxol reduced axon outgrowth in spinal cord neurons. To quantify the dynamic distribution of MTs in axons, we developed an automate...

In vitro studies conducted in Aplysia and chick sensory neurons indicate that in addition to microtubule assembly, long microtubules in the C-domain of the growth cone move forward as a coherent bundle during axonal elongation. Nonetheless, whether this mode of microtubule translocation contributes to growth cone motility in vivo is unknown. To address this question, we turned to the model syst...

It is increasingly evident that the actions of guidance factors depend critically on the cellular and molecular context in which they operate. For this reason we examined the growth cone morphology and behavior of thalamic fibers in the relatively natural environment of a slice preparation containing the entire pathway from thalamus to cortex. Axons were labeled with DiI crystals and imaged wit...

Social marketing faces significant barriers to growth because there is no clear understanding of what the field is and what its role should be in relation to other approaches to social change. However, growth is possible through increases in social marketing’s share of competition at the intervention, subject matter, product, and brand levels. The author proposes a specific social marketing bra...

Both organ growth and tumor growth are dependent upon a biased ratio of cell births to cell deaths; this ratio is independent of the frequency of mitosis. Thus, so-called growth factors that affect only the frequency of mitosis are not really growth factors. I shall advance two hypotheses: that the normal adult ratio of cell births to cell deaths is maintained by the activity of a factor or fac...

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Along the way, by way of illustration, I evaluate various players and teams with respect to baseadvance average. The evaluation of teams leads to further statistical comparisons. Here, the results are equally decisive in favor of base-advance average. For example, over the period 2000-2004, baseadvance average for-and-against predicts wins just as well as runs for-and-against. This is because, ...

INTRODUCTION Huxley, Mayr, Osmond, and Hoffer (1964) presented a hypothesis that schizophrenia is a genetic morphism (see Huxley, 1955). This is in general agreement with the proposition that all genetic characteristics which exist in a population at a frequency higher than can be maintained by mutation alone must be a morphism. The frequency of the morphic gene is the result of a balance betwe...