To date, methods of studying the effects drugs at molecular-genetic level are widely used in pediatric practice. The aim our work was to evaluate effectiveness effect β2-agonists on clinical course recurrent bronchial obstruction (RBO) children, depending variants polymorphism ADRB2 gene. salbutamol children with RBO and asthma(BA) evaluated distribution alleles genotypes Argl6Gly Gln27Glu gene...

Abstract Machine Learning for ligand based virtual screening (LB-VS) is an important in-silico tool discovering new drugs in a faster and cost-effective manner, especially emerging diseases such as COVID-19. In this paper, we propose general-purpose framework combining classical Support Vector Classifier algorithm with quantum kernel estimation LB-VS on real-world databases, argue favor of its ...

Behavioral processes have long been suspected to influence many health processes including effects on cancer. However, mechanisms underlying these observations are not fully understood. Recent work has demonstrated that chronic behavioral stress results in higher levels of tissue catecholamines, greater tumor burden, and a more invasive pattern of ovarian cancer growth in an orthotopic mouse mo...

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