BACKGROUND The quality-adjusted life-year (QALY) is a recognised outcome measure in health economic evaluations. QALY incorporates individual preferences and identifies health gains by combining mortality and morbidity into one single index number. A literature review was conducted to examine and discuss the use of QALYs to measure outcomes in telehealth evaluations. METHODS Evaluations were ...

AIMS To estimate the cost effectiveness of continuous subcutaneous insulin infusion (CSII) compared with multiple daily injections (MDI) for patients using insulin pumps. METHODS We constructed a Markov model to estimate the costs and outcomes for patients with insulin-dependent diabetes (IDDM) treated with CSII using an insulin pump compared with MDI. Key parameters were obtained from the pu...

Introduction Hepatocellular cancer (HCC) is a severe condition with poor prognosis and significant burden. Selective internal radiation therapy (SIRT) recommended as an alternative treatment option to overcome some limitations of current treatments. This analysis estimated the cost-effectiveness SIRT using Y-90 resin microspheres for unresectable HCC in Brazil. Methods study was conducted from ...

BACKGROUND & AIMS Availability of directly-acting antivirals (DAAs) has changed the treatment landscape of hepatitis C virus (HCV) infection. The high price of DAAs has restricted their use in several countries. However, in some countries such as India, generic DAAs are available at much cheaper price. This study examined whether generic DAAs could be cost-saving and how long it would take for ...

BACKGROUND Hodgkin's lymphoma patients have an elevated risk of developing lung cancer and may be targeted for lung cancer screening. We used a decision-analytic model to estimate the potential clinical benefits and cost-effectiveness of computed tomography (CT) screening for lung cancer in Hodgkin's lymphoma survivors. MATERIALS AND METHODS We developed a Markov decision-analytic model to co...

Population diets have impacts on both human and planetary health. This research aims to optimise a New Zealand (NZ) version of the EAT-Lancet diet model impact this population health if it was adopted in NZ. The optimisation methods used mathematical equations Excel ensure: met nutritional recommendations; diet-related greenhouse gas (GHG) emissions did not exceed NZ GHG boundary; costs baselin...

OBJECTIVES To assess changes in quality of life and costs of patients undergoing primary total hip replacement using the Exeter prosthesis compared with a hypothetical 'no surgery' group. DESIGN The incremental quality of life, quality-adjusted life years (QALYs) and cost of Exeter Primary Outcomes Study patients was compared with hypothetical 'no surgery' group over 5 years. Scores from annu...

Currently several tyrosine kinase inhibitors (TKIs) are approved for treatment of chronic myeloid leukemia (CML). Our goal was to identify the optimal sequential treatment strategy in terms of effectiveness and cost-effectiveness for CML patients within the US health care context. We evaluated 18 treatment strategies regarding survival, quality-adjusted survival, and costs. For model parameters...

In the past twenty-five years, egalitarian political philosophers have acknowledged the importance of injecting personal responsibility into egalitarian theory. In brief, the ethically attractive objective is to equalize opportunities for desirable conditions, such as health and earning capacity, rather than equalizing health status or earning capacities, across the members of a society. I prop...