introduction diabetes is one of the chronic diseases. it is not curable but it can be controlled. the study aimed to determine the effect of family centered empowerment model on the treatment regime of school age children. materials and methods a clinical trial study was carried out on the school age diabetes children and their families. considering ethical matter a total of 50 diabetics patien...

BACKGROUND Antiretroviral therapy (ART) extends life for patients with human immunodeficiency virus (HIV) infection. However, HIV treatment is lifelong, and adherence presents a special challenge. Suboptimal adherence to ART may lead to disease progression and virologic failure. Earlier studies with combination ART demonstrated that as much as 90%-95% adherence was needed to prevent disease pro...

There have been significant developments in effective human immunodeficiency virus treatment since the first antiretroviral was approved. A number of people living with not able to maintain viral suppression on oral therapy. long-acting monthly injectable regimen consisting cabotegravir and rilpivirine has approved for individuals who are virally suppressed. This is a good option those struggle...

BACKGROUND Therapeutic adherence of patients with chronic obstructive pulmonary disease (COPD) is poor. This study evaluated the effectiveness of a multifactorial intervention on improving the therapeutic adherence in chronic obstructive pulmonary disease (COPD) patients with scheduled inhalation therapy. METHODS The study design consisted of a randomised controlled trial in a primary care se...

BACKGROUND Traditional medication adherence measures do not account for the pharmacokinetic (PK) properties of the drugs, potentially misrepresenting true therapeutic exposure. METHODS In a population of HIV-infected Kenyan children on antiretroviral therapy including nevirapine (NVP), we used a one-compartment model with previously established PK parameters and Medication Event Monitoring Sy...

OBJECTIVES Simplification of antiretroviral therapy enhances a patient's adherence but a new formulation could also lead to new adverse events and changes in daily routine. This study compared medication adherence, tolerance and satisfaction among subjects switching from a two-tablet tenofovir/emtricitabine/efavirenz regimen to a one-tablet regimen. METHODS Clinical and sociodemographic data ...

BACKGROUND The advent of well-tolerated and effective anti-retroviral drugs against human immunodeficiency virus-1 (HIV-1) infection has been a major step forward that has achieved long-term survival in recent years. The number of HIV-1 infected patients who experience difficulty in swallowing tablets is expected to increase as the HIV-infected population advances in age or develops comorbiditi...

BACKGROUND Many patients have uncontrolled blood pressure (BP) because they are not taking medications as prescribed. Providers may have difficulty accurately assessing adherence. Providers need to assess medication adherence to decide whether to address uncontrolled BP by improving adherence to the current prescribed regimen or by intensifying the BP treatment regimen by increasing doses or ad...

Background: Adherence to the treatment regimen is among behaviors, which predict successful control of disease and decrease its intensity negative consequences, influenced by several factors. The patient's beliefs attitudes toward are effective factors in management adherence treatment, spiritual health one these influential variables. Objectives: aim this study was determine mediating role pat...

BACKGROUND Several measures using prescription data have been developed for estimating medication refill adherence. Few studies have made direct comparisons, and little is known about the accuracy of these measures in patients on a multiple-drug regimen. PURPOSE To compare different calculation methods using prescription data for assessing refill adherence. METHOD An observational cohort st...