Submit Manuscript | http://medcraveonline.com Abbreviations: NMD: Nonsense-Mediated mRNA Decay; ISE: Intronic Splicing Enhancer; ESE: Exonic Splicing Enhancer; ISS: Intronic Splicing Silencer; ESS: Exonic Splicing Silencer; PTC: Premature Termination Codon; ASC: Adenosquamous Carcinoma; NAS: Nonsense-associated Altered Splicing; NASRE: NonsenseAssociated Altered Splicing of a Remote Exon; ASO: ...

A 79-year old male with lung nodules on chest computed tomography underwent video-assisted thoracoscopic-surgical middle lobe wedge resection, with pathology proven adenosquamous carcinoma. Repeat video-assisted thoracoscopic-surgical-biopsy was performed for recurrent disease. Subsequent staging computed tomography revealed herniation of the gallbladder through the abdominal wall (Figs 1 and 2...

A 5-year-old girl with no preexisting systemic or CNS neoplasm presented with a large right temporal mass lesion, the histopathology of which proved to be a poorly differentiated adenosquamous carcinoma, a highly unusual primary intracranial tumor. The tumor recurred despite radical resection, chemotherapy, and radiation therapy.

Adenosquamous carcinoma (ASC) is a rare malignant tumor in the head and neck region and usually it occurs as a mucosal carcinoma. The World Health Organization classification1 shows this tumor as a variation of squamous cell carcinoma (SCC), whereas the Armed Forces Institute of Pathology (AFIP) classification2 categorized it as a salivary gland tumor. In the AFIP guidelines, the occurrence of ...

OBJECTIVE Primary papillary serous carcinoma (PPSC) of the cervix is rarely recognized, with the aggressive and unpredictable course. Here we report a case of primary adenosquamous papillary serous carcinoma of the cervix in a woman who underwent comprehensive treatment. CASE A 53-year-old woman presented with irregular vaginal bleeding in hospital. The patient with a diagnosis of PPSC by an ...

A 69-year-old woman from a kindred with familial atypical multiple mole melanoma and carrier of a germline mutation in CDKN2A, presented with abdominal pain caused by a solid-cystic pancreatic mass. The patient had an abdominal computed tomography three years before in which there was no evidence of pancreatic lesion. The endoscopic ultrasound guided fine needle aspiration showed adenocarcinoma...

From the Departments of *Surgery II, †Pathology and Laboratory Medicine and §Internal Medicine II, National Defense Medical College, Tokorozawa, Saitama, and the ‡Department of Surgery, International University of Health and Welfare Mita Hospital, Minato-ku, Tokyo, Japan M irizzi syndrome is a rare form of benign obstructive jaundice that is caused by a stone impacted either in the gallbladder ...

Cutaneous metastasis (CM) is an uncommon manifestation of visceral malignancies. Adenosquamous carcinoma of the gallbladder is a rare variation in gallbladder carcinoma (GBC), associated with worse prognosis. We present the case of a 56-year-old woman who presented with an inflamed lump on her abdominal wall. Computed tomography (CT) revealed a large mass from the gallbladder invading the abdom...

Objective. We report a rare and unusual case of bronchial carcinoma presenting with symptoms of complications of sinonasal disease. Case Report. A 66-year-old lady was referred with a 1-week history of progressive ocular pain, chemosis, and visual disturbance. Computed tomography of the paranasal sinuses revealed frontal and ethmoidal sinus opacification with orbital involvement consistent with...