Eccrine spiroadenocarcinoma is an extremely rare malignant eccrine gland tumor which may masquerade as other more common malignancies such as poorly differentiated squamous carcinoma or metastatic breast cancer. We report a case of an ulcerated axillary skin lesion with bulky adenopathy in a 77 year-old female with a prior history of ipsilateral triple negative breast carcinoma. The clear trans...

Here we report an 8 years old girl who had post natal growth deficiency, microcephaly, facial dysmorphism, partial syndactyly of the second and third toes, susceptibility to infections, leukocytosis, immunodeficiency, adenopathy, but now sign of telangiectasia, ataxia and in evolution developed malignancy. Chromosomal analysis showed anomalies. By combining clinical manifestations and laborator...

Chronic Fatigue Syndrome (CFS) is a recognised human illness [17] in which patients experience severe, debilitating fatigue for more than 6 months [39] , complicated by the fact that its diagnosis is largely based on subjective complaints in the absence of reproducibly reliable tests [3]. Symptoms include myalgias, arthralgias, sore throat, headache, adenopathy, poor functional status and neuro...

Their medical history of recurrent fever attacks started at the age of 14 and 6 months respectively. Fever was accompanied by cervical adenopathy, severe exudative pharyngitis, oral aphtosis, abdominal pain and diarrhoea, sometimes with bloody stools. At the age of 10 and 9 years, screening for autoinflammatory disorders was performed revealing a single mutated FMF gene (E148Q). Since they fulf...

Extraneural metastases from glioblastoma multiforme are rare. Spread to the extracranial head and neck may be evident on routine follow-up images of the original lesion. We present two cases, one with documented metastatic adenopathy in the head and neck from glioblastoma and the other with probable metastatic disease in a lymph node in which biopsy was not performed, and discuss probable mecha...