نتایج جستجو برای: acute transfusion reactions
تعداد نتایج: 681695 فیلتر نتایج به سال:
BACKGROUND Platelet concentrates contain soluble mediators derived from both platelets and contaminating leukocytes. During platelet transfusion these mediators are transferred, and transfusion-induced modulation of the cytokine network may then occur, possibly contributing to transfusion reactions, immunomodulation, or affecting residual leukemic cells. In this prospective observational study,...
BACKGROUND Transfusion of red blood cells (RBC) is recommended in septic shock and the majority of these patients receive RBC transfusion in the intensive care unit (ICU). However, benefit and harm of RBCs have not been established in this group of high-risk patients. METHODS/DESIGN The Transfusion Requirements in Septic Shock (TRISS) trial is a multicenter trial with assessor-blinded outcome...
• Bacterial sepsis from contaminated platelet transfusions continues to occur despite recent interventions; additional measures are needed. • STR to platelet transfusion is frequently not recognized or reported; use of recent AABB criteria showed highest diagnostic sensitivity. Septic transfusion reactions (STRs) resulting from transfusion of bacterially contaminated platelets are a major hazar...
INTRODUCTION Transfusion-related acute lung injury is emerging as a common cause of transfusion-related adverse events. However, awareness about this entity in the medical fraternity is low and it, consequently, remains a very under-reported and often an under-diagnosed complication of transfusion therapy. CASE PRESENTATION We report a case of a 46-year old woman who developed acute respirato...
BACKGROUND Allergic and febrile non-haemolytic transfusion reactions (NHTRs) are the two most common forms of transfusion reaction. Pretransfusion medication with anti-inflammatory drugs is used in NHTR prevention, however its efficacy and safety remains unclear. OBJECTIVES To assess the clinical effects and safety of pharmacological interventions for preventing NHTR in patients with and with...
By DONALD M. ERvIN, M.D., RICHARD M. CHRISTIAN, M.D., AND LAWRENCE E. YOUNG, M.D. H EMOLYTIC reactions resulting from transfusion of group 0 plasma into group A recipients, while not common, have been reported with increasing frequency during the past few years.’5 Reactions of this type are usually not as dramatic or as severe as those resulting from transfusion of incompatible whole blood and ...
BACKGROUND Calculation of desired whole blood transfusion volume relies on an estimate of an animal's circulating blood volume, generally accepted to be 0.08 L/kg or 8% of the animal's body weight in kilograms. OBJECTIVE To use packed cell volume before and after whole blood transfusion to evaluate the accuracy of a commonly used equation to predict packed cell volume after transfusion in sma...
BACKGROUND Although transfusion is a paramount life-saving therapy, there are multiple potential significant risks. Therefore, all adverse transfusion reaction (ATR) episodes require close monitoring. Using the computerized reporting system, we assessed the frequency and pattern of non-infectious ATRs. METHODS We analyzed two-year transfusion data from electronic medical records retrospective...
OBJECTIVE This study aimed to verify the performance of blood transfusion committees in transfusion services linked to the public blood bank network of the state of Minas Gerais. METHODS A cross-sectional observational study was conducted between 2007 and 2008 using questionnaires and proficiency tests to evaluate the reporting and investigation of transfusion reactions comparing transfusion ...
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