Acute ischemic stroke is a leading cause of death and major disability worldwide. Approximately 50% strokes are caused by atherothrombotic occlusion the cerebral arteries, antiplatelets mainstay secondary preventative treatment. Aspirin beneficial if given early, short‐term treatment using aspirin clopidogrel increasingly used for patients with intracranial atherosclerotic disease, minor stroke...

Acute stroke is increasingly recognised as one of the leading factors of morbidity and mortality worldwide. Its economical burden is among the highest of all diseases. Ischaemic stroke is by far the most frequent subtype of acute stroke. More than 80% of all stroke patients suffer from focal ischaemia [Bonita, 1992]. Over the past decades, acute stroke has increasingly been recognised as a medi...

OBJECTIVE To study the workload of and use of acute intervention within an established acute stroke service, the Calgary Stroke Programme (CSP). METHODS Prospective record of all acute referrals, diagnoses, and management decisions over a 4 month period. RESULTS The CSP received 572 referrals (median: 32 per week), 88% of which were made between 7 am and midnight. Of the 427 patients seen i...

OBJECTIVE To help family physicians who care for patients with acute stroke or who are involved in planning service delivery or resource allocation to understand recent developments in acute stroke care. QUALITY OF EVIDENCE A MEDLINE search indicated that most data were derived from well designed, randomized, double-blind, placebo-controlled trials, including all the largest international stu...

PURPOSE Thrombolysis with tissue plasminogen activator (rtPA) is currently used throughout the world in acute ischaemic stroke management. In this review, we will explore the status of our current knowledge about the effects of rtPA on specific rehabilitation domains and highlight some key knowledge gaps. METHODS Narrative review of the larger clinical and postmarketing surveillance studies. ...

In recent years, several landmark trials have transformed acute ischemic stroke care. The most dramatic results from the field of acute endovascular intervention demonstrate unequivocal benefit for a select group of patients with moderate to severe deficits presenting within 7 hours from onset and with occlusions of proximal arteries in the anterior circulation. In addition, technological advan...

stroke patients with proximal occlusions of the main stems of cerebral arteries are no optimal candidates for i. v. thrombolysis. for many years interventional stroke treatment could not be established as alternative. this changed with the introduction of stent retrievers and flexible large lumen aspiration catheters. randomized trials now proved a significant benefit from intervention for a wi...

Concurrent acute ischemic stroke and acute myocardial infarction is an uncommon medical emergency condition. The challenge for the physicians regarding the management of this situation is paramount since early management of one condition will inevitably delay the other. We present two illustrative cases of "hyperacute simultaneous cardiocerebral infarction" who presented with simultaneous cardi...

In the beginning of this century, a dramatic increase of age-related serious neurological disorders including stroke and vascular dementia is expected in concomitant with continuous increase of older-age population. In order to harmonize several strategies to combat these neurological disorders in a reasonable way, it is critically important to promote lifetime education of stroke medicine for ...

Introduction Stroke is a continuum spectrum of complications related to the cerebrovascular event. Economic evaluation usually estimates costs incurred during acute management phase. Costs for managing post stroke patients at Specialist clinic setting and outpatient rehabilitation are of interest for developing countries which largely provide this type of service. We aim to determine costs for ...