A ntithrombotic treatment for acute deep vein thrombosis (DVT) or pulmonary embolism (PE) should consist of a therapeutic dose of low molecular weight heparin (LMWH) for o5 days, followed by a vitamin K antagonist for o3 months. LMWH has simplified the initial management of DVT because it is at least as effective and safe as unfractionated heparin and can be administered in fixed subcutaneous d...

Background. Postthrombotic syndrome (PTS) is a burdensome and costly complication of deep vein thrombosis (DVT). Up to 50% of patients with DVT will develop the disease within two years following the diagnosis of acute DVT. Various risk factors for developing PTS have been identified and different modalities have been used to prevent its development. Compression stockings have been studied for ...

INTRODUCTION We examined the cost-effectiveness of the three different D-dimer measurements in the screening of DVT in models with and without calculation of pre-test probability (PTP) score. Moreover, we calculated the minimal cost in DVT detection. MATERIAL AND METHODS In the group of 192 patients with clinically suspected acute DVT, we examined the three different D-dimer measurements (Inn...

BACKGROUND Our objective was to systematically review the incidence of deep vein thrombosis (DVT) and the efficacy of thromboprophylaxis in critically ill adults, including patients admitted to intensive care units and following trauma, neurosurgery, or spinal cord injury. METHODS Two authors independently searched MEDLINE, EMBASE, abstract databases, and the Cochrane database. Data were extr...

Background. The objective of this study was to develop a simple ultrasound method for measuring thrombus regression in patients with proximal deep-vein thrombosis (DVT) and to test its utility for the detection of DVT recurrence. Methods and Resuls. The study comprised a cross-sectional survey and a prospective investigation (149 and 145 patients, respectively). In both phases, the normalizatio...

STUDY OBJECTIVES To develop and to evaluate selection criteria for outpatient management of deep venous thrombosis (DVT). DESIGN We developed outpatient treatment eligibility criteria that incorporated demographic and clinical data. We aimed to exclude patients at high risk for bleeding or recurrent clotting, as well as those with pulmonary embolism, limited cardiopulmonary reserve, or need f...

Background. The types of ultrasonographic findings observed in patients referred for color duplex Doppler ultrasonography (CDD-US) of veins of lower extremities are presented in this paper. Patients and methods. During 27 months, 934 patients were examined. Among these, 663 were women (71 %) and 271 men (29 %), with the age range 19-86 (mean 58.4) years. Color Doppler scanners Acuson 128 XP 10,...

AIM/BACKGROUND Treatment of DVT with LMWHs has been shown recently to be as effective as UFH with suggested lower costs. This study was conducted to determine and compare the cost of in-patient hospital treatment versus outpatient hospital treatment of patients with DVT. METHOD All adult patients with acute proximal DVT referred to the Emergency Department of King Khalid University Hospital, ...

OBJECTIVES Evaluation of the effectiveness and safety of the low molecular weight heparin (LMWH) tinzaparin versus unfractionated heparin (UFH) followed by acenocoumarol in proximal deep venous thrombosis (DVT). DESIGN Prospective, randomized clinical trial. MATERIAL AND METHODS Consecutive patients (n=108) with acute leg DVT, confirmed by duplex, were randomized to either tinzaparin alone ...