background: brucellosis can involve almost any organ system and may present with a broad spectrum of clinical presentations. in this study we present a case of deep vein thrombosis due to human brucellosis. case presentation: a 15 year old boy presented acute pain and swelling in his left thigh. when admitted to the hospital in june 2011, he complained of fever, chills and lowers extremity pain...

human brucellosis is common in developing countries and is a multi-system disease with a broad spectrum of clinical manifestations. cutaneous lesions associated with brucellosis have been rarely reported in the literature. here we present a case of a 32-year-old man with history of consumption of cheese made from raw milk seen with occurrence of pancytopenia and diffuse maculopapular rash durin...

Background: Brucella is a gram-negative bacterium, causing acute and chronic infection in humans and animals. Cell-mediated immunity is the main protective immune response against Brucella spp. Activation of macrophages by IFN-γ and generation of reactive oxygen intermediates and nitric oxide are the main immunologic mechanisms responsible for control of Brucella infection. Objective: To invest...

Purpose. Acute scrotal pain as the first symptom of brucellosis is rarely observed. We aimed to evaluate the data of male patients with brucellosis and epididymoorchitis as the initial diagnosis. Material and Methods. The data of seven patients presented with testicular pain, hyperemia, swelling, and increased fever were reviewed. Concomitant focal diseases as well as clinical, laboratory, and ...

The use of enzyme-linked immunosorbent assay (ELISA) for the detection of IgG and IgM antibodies antibrucella has become widespread in the diagnosis of human brucellosis. IgM anti-Brucella antibodies are indicative of acute infection. Between 2009-2013, 5307 patients were evaluated for serologic diagnosis at the Microbiology Laboratory of the Albacete General Hospital. A ELISA IgM-positive, IgG...

background: increased levels of interleukin-8 (il-8) and interleukin-6 (il-6) in acute human brucellosis have been reported. previous studies have shown that the production and level of il-6 and il-8 cytokines are associated with the polymorphism of the encoding genes. objective: to investigate the probable association between il-6 (-174 c/g) and il-8 (-251 a/t) gene polymorphisms and susceptib...

Brucellosis is an acute and chronic disease of cattle and can be transmitted to human beings. This disease is associated with numerous clinical manifestations and the rate of incidence of its skin complications is 5% in the affected patients. One of its rare skin complications is brucella abscess. In this study a 9-years old girl is presented with skin abscess of the posterior part of right ank...

Brucellosis is an endemic disease in developing countries. The most commonly observed complications include bone-joint involvement, particularly sacroiliitis and spondylitis. Epidural abscesses caused by brucellosis are a rare complication. We describe the case of a 33-year-old man presenting with high fever, back pain, and weakness. At physical examination, the patient was found to be parapare...