Simian foamy virus type 1 (SFV-1), a member of the Spumavirinae subfamily of retroviruses, encodes a transcriptional transactivator (taf) that strongly augments gene expression directed by the viral long terminal repeat (LTR) (A. Mergia, K. E. S. Shaw, E. Pratt-Lowe, P. A. Barry, and P. A. Luciw, J. Virol. 65:2903-2909, 1991). This report describes cis-acting regulatory elements in the LTR that...

PURPOSE To evaluate and compare the intraocular pressure (IOP) reduction efficacy and safety between the ophthalmic solutions 0.005% latanoprost (Lat) and 0.0015% tafluprost (Taf) in Japanese patients with normal-tension glaucoma (NTG). METHODS In this randomized nonmasked study, we prospectively enrolled 30 Japanese NTG patients who had used Lat monotherapy for more than 4 weeks, and randoml...

Road detection from images has emerged as an important way to obtain road information, thereby gaining much attention in recent years. However, most existing methods only focus on extracting information single temporal intensity images, which may cause a decrease image resolution due the use of spatial filter avoid coherent speckle noises. Some newly developed take into account multi-temporal p...

113LB [26] aimed at establishing the virologicalnon-inferiority of the TAF formulation compared to the TDFformulation. The primary endpoint was the proportion of peoplewith a viral load (VL) ≤50 copies/mL at 48 weeks using the FDAsnapshot endpoint. Median ages of the two groups were 33 and35 years, 85% in both groups were men, about 25% black and19% Hispanic/Latino. Medi...

ETHNOPHARMACOLOGICAL RELEVANCE Peganum harmala is used in traditional medicine to treat a number of diseases including cancer. Our preliminary studies show that the alkaloidal extract of PH seed is cytotoxic to several tumor cell lines in vitro and has antitumor effect in a tumor model in vivo. The present investigation was aimed at extending our previous studies in identifying the components i...

Abstract Background Solid organ transplantation (SOT) is the definitive treatment for end-organ failure in HIV-positive recipients. Bictegravir (BIC) or dolutegravir (DTG) based antiretroviral therapy (ART) preferred ART due to high efficacy, excellent tolerability and minimal drug interactions, yet there a paucity of data on these second generation integrase inhibitors (INSTIs) SOT. We report ...

This study examined differences in the appraisal and thought control strategies associated with the perceived control of unwanted sexual and non-sexual intrusive thoughts. Eleven appraisal dimensions, subjective physiological arousal and 10 thought control strategies were measured in 171 university students who were administered the Revised Obsessive Intrusions Inventory-Sex Version, a self-rep...

This paper investigates the effectiveness of one of the Federal Reserve’s unconventional monetary policy tools, the term auction facility (TAF). At issue is whether the TAF reduced the spread between the London interbank offered rate (LIBOR) rates and equivalent-term Treasury rates by reducing the liquidity premium embedded in LIBOR rates. This paper suggests that rather than reducing the liqui...

We evaluated comparatively the mechanical strength in three kinds of surgical fixation techniques for canine atlantoaxial joint. Atlantoaxial plate fixation (APF), polymethylmethacrylate (PMMA) fixation (PMF) and transarticular fixation (TAF) were applied to the atlas and axis harvested from healthy beagle dogs, and then, the specimens were tested. The PMF group had significantly higher resista...