Microbial pathogens are developing resistance against existing antibiotics, stressing the urgency for discovery of new therapeutic compounds. Actinomycetes, alone produce 70-80% of the available antibiotics. The chances of isolating undiscovered strains from the terrestrial habitats have diminished so that the search for novel products has switched to rare genera of actinomycetes from normal ha...

Colonization of host plants by microbial symbionts and avirulent parasites often elicits physiological modifications such as localized and systemic disease resistance1–4) and drought or dehydration tolerance5–7). Among such microbes, soil-inhabiting actinomycetes have attracted much attention as potential biocontrol agents in agriculture because of their ability to produce a variety of antibiot...

The development of the eco friendly procedures makes nanoparticles as the rapidly growing field of nanotechnology. Amongst, the silver nanoparticles have become prominent in the field of medicine to their peculiar antimicrobial properties. In the present study we suggest an eco friendly procedure of extracellular synthesis of silver nanoparticles with an average sizes of 5-50nm using an Act...

The development of the eco friendly procedures makes nanoparticles as the rapidly growing field of nanotechnology. Amongst, the silver nanoparticles have become prominent in the field of medicine to their peculiar antimicrobial properties. In the present study we suggest an eco friendly procedure of extracellular synthesis of silver nanoparticles with an average sizes of 5-50nm using an Act...

Interspecies interaction of actinomycetes will express new gene clusters and may therefore affect the pigmentation, sporulation and production of secondary metabolites. Actinomycetes strains were isolated from Howze Soltan Salt Lake. Binary actinomycete interaction assay was conducted to evaluate its effect on colony morphology and antibiotic production. The molecular identification of the indu...

Thermophilic actinomycetes, associated with a hypersensitivity pneumonitis, may be found in compost but also have been detected in heating systems of office buildings. This study was designed to determine whether these organisms were present in residential heating systems. Furnace dust or humidifier water of 12 of 20 homes contained thermophilic actinomycetes, indicating that the organisms may ...

Actinobacteria (actinomycetes) have been received much attention, as these bacteria pro‐ duce a variety of natural drugs and other bioactive metabolites. The distribution of acti‐ nomycetes in various natural habitats, including soil, ocean, extreme environments, plant, lichens and animals, is described. The collection and pretreatment of test samples from different sources, design principle of...

Genomic sequence data have revealed the presence of a large fraction of putatively silent biosynthetic gene clusters in the genomes of actinomycetes that encode for secondary metabolites, which are not detected under standard fermentation conditions. This review focuses on the effects of biological (co-cultivation), chemical, as well as molecular elicitation on secondary metabolism in actinomyc...

Effluent of various industries contain number of inhibitory substances which are continuously added in sea via river and results in water pollution. There is need to degrade the organic content to abate water pollution. In the present study, actinomycetes were isolated on glycerol aspargine agar from marine sample of Calangut beach, Goa. The isolates were tested for their potential to tolerate ...

Actinomycetes, filamentous actinobacteria found in numerous ecosystems around the globe, produce a wide range of clinically useful natural products (NP). In natural environments, actinomycetes live in dynamic communities where environmental cues and ecological interactions likely influence NP biosynthesis. Our current understating of these cues, and the ecological roles of NP, is in its infancy...