Cytoskeleton is responsible for fundamental cellular processes and functions. The filamentous actin (F-actin) a key constituent of the cytoskeleton system which intrinsically viscoelastic greatly determines mechanical properties cells. organization polymerization F-actin are relevant to viscoelasticity distribution migration living cells responding pH microenvironments. Recently, progression in...

Treatment of hepatocyte-hepatoma hybrid cells with Clostridium botulinum C2 toxin led to a 167% increase in monomeric globular actin (G-actin) and to a 57% decrease in filamentous actin (F-actin) within 2 h. Simultaneously, the level of actin mRNA was specifically decreased to 49% and actin synthesis was significantly diminished. In contrast, treatment of hybrid cells with phalloidin led to a d...

Polarization of the actin cytoskeleton is vital for collective migration cells in vivo. During invasive border cell Drosophila, polarization directly controlled by Hippo signaling complex, which resides at contacts between cluster. Here, we identify, a genetic screen deubiquitinating enzymes involved migration, an essential role nonstop/USP22 expression pathway components expanded and merlin. L...

To figure out the pathway by which epigallocatechin gallate restrains angiogenesis and glycolysis in colorectal cancer through circular ribonucleic acid (actin gamma 2)/microRNA-370-5p axis. Detection of actin 2 microRNA-370-5p patient tissues cells vascular endothelial growth factor A was conducted. Cell viability proliferation, angiogenesis, glucose lactate were examined. Circular microRNA-37...

myoepitheliomas are benign tumors which account for less than 1% of all salivary gland tumors. in this article, we report the clinical, pathologic, and immunohistochemical features of plasmacytoid myoepithelioma of the hard palate in a 73-year-old man having a painless hard palate mass with progressive growth for one month who was admitted in alzahra hospital of isfahan university of medical sc...

Objectives To observe changes in actin and dendritic spines the hippocampus after propofol anesthesia, to evaluate role of these subsequent learning impairment both young (3-month-old) aged (20-month-old) male rats. Methods The shuttle box test was used from 1, 3, 7, or 14 days anesthesia. Both F-actin content hippocampal CA1 region were observed using immunofluorescent staining western blot as...