The C═N bond is a critical structural piece of many N-donor ligand scaffolds and central to the properties reactivity important coordination complexes. For example, units play key role in “redox non-innocence” α-diimine complexes making charge-transfer excited-state character available N-heterocyclic ligands such as bipyridine. In N-heterocycles like pyridine, benzannulation can be used extend ...

Compounds with planar triple ring systems such as acridine orange, 9-amino acridine, 9-amino-1,2,3, 4-tetrahydroacridine (tacrine), 6,9-diamino-2-ethoxyacridine lactate monohydrate (DE-acridine), 6-chloro-9-(3'-diethylamino-2'-hydroxypropylamino)-2-methoxyacridine 2 HCI (CDM-acridine), quinacrine, 6-chloro-9(4'diethylamino1'-methylbutylamino) .2-methoxy. 1, 10-diazaanthracene (CDM 1, 10-diazaan...

In the crystal structure of the title compound, C(27)H(20)NO(2) (+)·CF(3)SO(3) (-), the cations form inversion dimers through π-π inter-actions between the acridine ring systems [centroid-centroid distances = 3.668 (2)-3.994 (2) Å]. These dimers are further linked by C-H⋯O and C-H⋯π inter-actions. The cation and the anion are connected by C-H⋯O inter-actions. The mean plane of the acridine ring...

Sir,?I have read with great interest the article, 'A Case of Giardiasis' by H. S. Andleigh, in the June 1942 number of the Indian Medical Gazette. The author reports the striking results of treating a case of giardiasis with atebrin but does not offer any explanation for this, at first sight, surprising result. As this article may lead to further experiments with this method I may perhaps be pe...

In view of the importance of a rapid aetiological diagnosis in septicaemia, we compared the results of subculture, Gram staining and acridine orange staining in the detection of positive blood cultures. The study was based on 1013 blood cultures of which 138 were positive by culture. The three techniques were applied 12 h after the specimen was taken in 210 instances, at 24 h in 540 instances a...

A series of novel potential DNA bis-intercalators were designed and synthesized, in which two glucuronic acids were linked by ethylenediamine, and the glucuronic acid was coupled with various chromophores, including quinoline, acridine, indole and purine, at the C-1 position. The preliminary binding properties of these compounds to calf thymus DNA (CT-DNA) have been investigated by UV-absorptio...