نتایج جستجو برای: acpa
تعداد نتایج: 903 فیلتر نتایج به سال:
OBJECTIVE To group HLA-DRB1 alleles based on acid-base properties of amino acids at positions 13, 70 and 71 and analyse their association with the presence of anticitrullinated peptide antibodies (ACPA) and structural progression in 2 cohorts of early rheumatoid arthritis (RA). METHODS Patients with RA (N=612) from ESPOIR cohort and from EAC cohort (n=624) were genotyped for HLA-DRB1 alleles....
یادگیری فرآیندی است که در آن دانش و اطلاعاتی را درباره جهان به دست می آوریم. استفاده از آگونیست و آنتاگونیست های انتخابی سروتونین مشخص کرده است که این مونوآمین در یادگیری و حافظه دخیل است. ناحیه تگمنتوم شکمی از هسته رافه میانی و پشتی عصب های سروتونرژیک دریافت می کند. اندوکانابینوئیدها در فرآیندهای رفتاری مثل حرکت، اضطراب، یادگیری و حافظه - - نقش تنظیمی عصبی مهمی دارند. در این مطالعه از موش ...
Background In rheumatoid arthritis (RA) many patients harbor autoantibodies against post translationally modified proteins (anti-modified protein antibodies (AMPA)): anti-citrullinated (ACPA), anti-carbamylated (anti-CarP) and anti-acetylated (AAPA). All three AMPA have been described to be associated with an increase in radiographic joint damage ACPA also a lower chance of obtaining sustained ...
A 73-year-old man with a history of myasthenia gravis (MG) was diagnosed with rheumatoid arthritis (RA) based on a history of polyarthritis and positivity for anti-citrullinated protein antibodies (ACPA). He presented with a high level of serum vascular endothelial growth factor (VEGF) and RS3PE syndrome-like pitting edema in the extremities, which improved following treatment with low-dose pre...
BACKGROUND Follicular structures resembling germinal centres (GCs) that are characterized by follicular dendritic cell (FDC) networks have long been recognized in chronically inflamed tissues in autoimmune diseases, including the synovium of rheumatoid arthritis (RA). However, it is debated whether these ectopic structures promote autoimmunity and chronic inflammation driving the production of ...
Holographic transmission gratings with a spatial frequency of 2658 lines/mm and reflection gratings with a spatial frequency of 4553 lines/mm were stored in a polyvinyl alcohol (PVA)/acrylamide (AA) based photopolymer. This material can reach diffraction efficiencies close to 100% for spatial frequencies about 1000 lines/mm. However, for higher spatial frequencies, the diffraction efficiency de...
BACKGROUND This article provides an overview of modern serological diagnostic testing for rheumatoid arthritis (RA) involving the detection of antibodies against citrullinated peptides/proteins (ACPA). Recommendations are also given for differential diagnosis and sequential testing in rheumatoid arthritis, with a view towards improving early diagnosis, so that irreparable joint damage can be av...
Anti-citrullinated peptide antibodies (ACPA) have a very high specificity for rheumatoid arthritis, much more than that of the rheumatoid factor. In addition, ACPA can be found in sera in the pre-clinical phase, are associated with more severe joint destruction and with higher disease activity. In recent years, keeping pace with new knowledge and with progress made in the antigenic composition ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید