نتایج جستجو برای: acidic medium

تعداد نتایج: 268647  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1981
R S Morrison J de Vellis

Astrocytes purified from primary cultures of neonatal rat cerebrum can now be grown in a synthetic medium supplemented with putrescine, prostaglandin F2 alpha, insulin, fibroblast growth factor, and hydrocortisone. These five supplements have a marked synergistic effect on growth when used in combination but have little effect when used individually. Astrocytes grown in the defined medium exhib...

Journal: :Cancer research 1990
P Montcourrier P H Mangeat G Salazar M Morisset A Sahuquet H Rochefort

In breast cancer cell lines, pro-cathepsin D is synthesized in excess and abnormally processed, resulting in its slower maturation and increased secretion into the culture medium. Since this lysosomal protease is only active at acidic pH, we have searched for acidic compartments other than lysosomes where cathepsin D might be active when MCF7 cells are plated on corneal extracellular matrix. We...

Journal: :Metal-Based Drugs 1999
Iztok Turel Janez Košmrlj Bjørn Andersen Einar Sletten

A proton NMR study was performed on the copper(ll)-ciprofloxacin system. The proton relaxation times (T(1)) were determined from the titration data in acidic and basic media. In acidic medium the H5 signal is dramatically affected and it is assumed that copper is bonded to the quinolone through carbonyl and one of the carboxyl oxygens. Such bonding is in agreement with the X-ray literature data...

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