We describe the development of a Cyclotron Mass Spectrometer (CMS) for the detection of trace amounts of rare isotopes. A compact low energy cyclotron optimized for high mass resolution has been designed and fabricated. The CMS has high sensitivity and is designed to measure 14C at abundances of 10-12. A novel feature of the CMS is the use of permanent magnets to energize the 30 cm diameter iro...

BACKGROUND Accelerator mass spectrometry (AMS) is a sensitive isotope ratio technique used in drug development that allows for small levels of 14C-drug to be administered to humans, thereby removing regulatory hurdles associated with radiotracer studies. AMS uses innovative study designs to obtain pharmacokinetic and metabolism data. OBJECTIVE This review addresses the metabolism and pharmaco...

The dynamics and engineering of a spiral slingatron mass accelerator are described together with the status of experiments. The potential utility of this mechanical device for space launch applications is discussed.

In 1988, Carbon-14 findings from three Accelerator Mass Spectrometer (AMS) Labs independently dated a sample removed from the Shroud of Turin: unarguably the most widely studied linen cloth in history. The dates reported ranged between 126