groundwater is among the most important resources of drinking water supply ofthe worldwide population. use of recharge area is one of the methods for artificiallyrecharging groundwater. selection of suitable sites for artificial recharge is very importantand must be carried out accurately. there are different types of land use, only rangelandsare appropriate for artificial recharge because of t...

[1] Groundwater recharge is likely to be affected by climate change. In semiarid regions where groundwater resources are often critical, annual recharge rates are typically small and most recharge occurs episodically. Such episodic recharge is uncertain and difficult to predict. This paper analyzes the impacts of different climate predictions on diffuse episodic recharge at a low‐relief semiari...

The clinical effectiveness of adriamycin (ADR), a potent chemotherapeutic, is known to be limited by severe cardiotoxic side effects. However, the effect of ADR on brain tissue is not well understood. It is generally thought that ADR is not toxic to the brain because ADR does not pass the blood-brain barrier. The present study demonstrates that ADR autofluorescence was detected only in areas of...

Driverless plug-in electric vehicles (DPEVs) have attracted a growing attention in transport engineering due to their low environmental impact and increased level of automation. When compared to regular internal combustion engine vehicles, DPEVs have two characteristics: 1) DPEVs require a higher frequency of recharge operations; 2) DPEVs are controlled by predetermined intelligent algorithms, ...

Earlier this year, Sydney officially opened its new water desalination plant, the largest so far in Australia and driven by renewable wind power. It is the third to open in the country but will soon be overtaken by further new desalination plants. Australia's response to the growing demand for water and the increasing scarcity and unpredictability of conventional supplies is being echoed around...

Vietnamese Mekong Delta. This study investigates the trends of groundwater levels (GWLs), memory effect alluvial aquifers, and response times between surface water across Delta (VMD). Trend analysis, auto- cross-correlation, time-series decomposition were applied within a moving window approach to examine non-stationary behavior. Our revealed an effective connection shallowest aquifer unit (Hol...

Abstract The Chalk is an unusual karst aquifer with limited cave development, but extensive networks of smaller solutional conduits and fissures enabling rapid groundwater flow. Small-scale features (stream sinks, dolines, dissolution pipes, springs) are common, hundreds stream sinks recorded. Tracer velocities from 27 connections between springs have median mean 4700 4600 m d −1 . Tests to abs...

Objective(s): Acquisition of TNF-α resistance plays role in the onset and growth of malignant tumors. Previous studies have demonstrated that MCF-7 cell line and its doxorubicin resistant variant MCF-7/Adr are resistant against the cytotoxic effects of TNF-α. In this study, we investigated the role of Akt activation in resistance of MCF-7 and MCF-7/Adr against TNF-α cytotoxicity. Materials and ...

Adriamycin (ADR)-resistant sublines of B16-BL6 mouse melanoma selected by exposure to increasing concentrations of ADR were characterized in vitro for growth properties and in vivo for tumorigenicity and pulmonary metastases. The progressively resistant sublines adapted to grow in the presence of 0.025, 0.05, 0.1, and 0.25 microgram/ml ADR in monolayer culture were found to be 5-, 10-, 20-, and...

Resistance to Adriamycin (ADR) is frequently dependent upon en hanced efflux associated with the expression of the IV!DR1-encoded P membrane glycoprotein. Since enhanced expression of the MDR1 gene in ADR-resistant cells may be the result of spontaneous genetic mutation or amplification, it is presumed to be relatively stable and unalterable. Yet, reducing ADR efflux could increase sensitivity,...