نتایج جستجو برای: abc transporters

تعداد نتایج: 35243  

2014
Robert M. Greenberg

Praziquantel (PZQ) is essentially the only drug currently available for treatment and control of schistosomiasis, a disease affecting hundreds of millions worldwide. Though highly effective overall, PZQ has limitations, most notably its significant lack of activity against immature schistosomes. Furthermore, the availability of only a single drug for a disease of this magnitude makes reports of...

Journal: :Essays in Biochemistry 2011

Journal: :Structure 2013
Yaroslav Tsybovsky Tivadar Orban Robert S Molday Derek Taylor Krzysztof Palczewski

ATP-binding cassette (ABC) transporters use ATP to translocate various substrates across cellular membranes. Several members of subfamily A of mammalian ABC transporters are associated with severe health disorders, but their unusual complexity and large size have so far precluded structural characterization. ABCA4 is localized to the discs of vertebrate photoreceptor outer segments. This protei...

Journal: :Naunyn-Schmiedeberg's Archives of Pharmacology 2006

Journal: :Nature Reviews Molecular Cell Biology 2009

Journal: :Plant Signaling & Behavior 2008

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