[1] We present evidence for the existence of an Australian-Antarctic Mantle Anomaly (AAMA), which trends northwest-southeast (NW-SE) through the Australian-Antarctic Discordance (AAD) on the Southeast Indian Ridge (SEIR), is confined to the upper 120 km of the mantle beneath the AAD, and dips shallowly to the west so that it extends to a depth of about 150 km west of the AAD. Average temperatur...

BACKGROUND We previously demonstrated that treatment with antiarrhythmic drugs (AADs) during the first 6 weeks after atrial fibrillation (AF) ablation reduces the incidence of clinically significant atrial arrhythmias and need for cardioversion or hospitalization for arrhythmia management. Whether early rhythm suppression decreases longer-term arrhythmia recurrence is unknown. We now report the...

BACKGROUND Antibiotic prescribing rates in care homes are higher than in the general population. Antibiotics disrupt the normal gut flora, sometimes causing antibiotic-associated diarrhoea (AAD). Clostridium difficile (Hall and O'Toole 1935) Prévot 1938 is the most commonly identified cause of AAD. Little is known either about the frequency or type of antibiotics prescribed in care homes or abo...

UNLABELLED Imaging with (18)F-FDG PET/CT is able to reveal vascular inflammation, and several studies have shown that increased (18)F-FDG uptake in carotid artery plaques can qualify the degree of atherosclerotic inflammation. However, clinical assessment of acute aortic dissection (AAD) by PET/CT remains largely unexplored. This study aimed to investigate the use of (18)F-FDG PET/CT to predict...

Inhibitors for glutathione S-transferase (GST) iso-enzymes from rat liver with high affinity for the glutathione-binding site (G-site) have been developed. In previous studies, a model was described for the G-site of GST (Adang, A. E. P., Brussee, J., van der Gen, A., and Mulder, G. J. (1990) Biochem. J. 269, 47-54) in terms of essential and nonessential interactions between groups in glutathio...

A 7.7-kilobase BamHI fragment was cloned from the transconjugant of a clinical isolate of Escherichia coli containing a 120-kilobase multiresistance IncC plasmid. The recombinant plasmid conferred resistance to kanamycin, gentamicin, tobramycin, sulfamethoxazole, and trimethoprim. This clone was used to generate a series of subclones from which a 2.0-kilobase BamHI-HindIII probe containing a ge...

Evaluation of the acrosome reaction can shed light on the fertilising competence of spermatozoa. To eliminate false-positive results when evaluating the acrosome status of human sperm cells, two viability probes propidium iodide (PI) and 7-amino-actinomycin D (7-AAD) were compared for their ability to stain nonviable cells post-fixation and permeabilisation. Both the mean fluorescence and % dea...

Segmentation defects are often seen with congenital atlantoaxial dislocation (AAD) though an associated absence of posterior arch of C2 and butterfly C3 is rare. Apart from rarity, the combination of formation and segmentation defects adds to the management dilemma. We report a case of AAD with assimilated atlas, absent C2 posterior arch, C3 butterfly vertebra with floating posterior elements, ...

Acute aortic dissection (AAD) is an uncommon clinical picture with a high mortality rate. Early diagnosis and treatment are important in decreasing the mortality. Clasically, AAD is characterized by a severe sudden onset pain of the chest, back, and abdomen. However, the patients with AAD may admit with a variety of different clinical findings as due to level of dissection in the aorta. In this...

Background The type “A” aortic dissection (AAD) is a dangerous acute complication of the Marfan syndrome. Not only the native outcome of the AAD is life threatening, but even the surgical treatment of this complication is risky. Despite the improving surgical experience and the more effective cerebral and myocardial protection the lethality of the surgical treatment of AAD at Marfan patients is...