نتایج جستجو برای: 99mtc hynic toc

تعداد نتایج: 7807  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی شاهرود - دانشکده فیزیک 1394

از رادیوداروی99mtc به عنوان اسب بارکش بخش پزشکی هسته ای نام می برند. این رادیودارو از دوشیدن ژنراتور99mo -99mtc بدست می آید. چشمه ی این رادیودارو99mo است که درون ستون استوانه ای شکل ژنراتور قرار می گیرد و پس از نیمه عمر واپاشی خود 99mtc حاصل می شود. عواملی روی کارکرد ستون درون ژنراتور تأثیرگذارند که باعث می شود ستون در هنگام دوشیدن ژنراتور و در هنگام جداسازی همه ی 99mo را جذب نکند و محلول 99mtc...

Journal: :Molecules 2016
Zhide Guo Mengna Gao Manli Song Changrong Shi Pu Zhang Duo Xu Linyi You Rongqiang Zhuang Xinhui Su Ting Liu Jin Du Xianzhong Zhang

The folate receptor (FR) is overexpressed in a wide variety of human tumors. In our study, the multimeric concept was used to synthesize a dimeric folate derivative via a click reaction. The novel folate derivative (HYNIC-D₁-FA₂) was radiolabeled with (99m)Tc using tricine and trisodium triphenylphosphine-3,3',3″-trisulfonate (TPPTS) as coligands ((99m)Tc-HYNIC-D₁-FA₂) and its in vitro physicoc...

2015
Diana Loreta Paun Lavinia Vija Emilia Stan Alexandra Banica Elena Bobeica Dana Terzea Catalina Poiana Corin Badiu Sorin Paun

BACKGROUND Ectopic production of adrenocorticotropic hormone (ACTH) by neuroendocrine tumours (NET) is a rare condition, occult presentations often hampering the diagnosis. Although NET are relatively frequent in the ileon and Meckel diverticulum, we describe the first Cushing's syndrome due to ectopic adrenocorticotropic syndrome (CS-EAS) arising from a Meckel diverticulum. CASE PRESENTATION...

Journal: : 2022

Objective: The development of new radiopharmaceuticals capable specifically imaging cancer is an important research area. For this reason, the aim study to investigate cell binding novel developed nanoradiopharmaceutical ([99mTc]Tc-nab-PTX) on HT-29 line (human colorectal adenocarcinoma cells).
 Material and Method: In study, nab-PTX was labeled with [99mTc]Tc, labeling efficiency in vitro...

Journal: :Current pharmaceutical design 2013
Nathalie Matusiak Aren van Waarde Rainer Bischoff Ruth Oltenfreiter Christophe van de Wiele Rudi A J O Dierckx Philip H Elsinga

Dysregulation of matrix metalloproteinase (MMP) activity can lead to a wide range of disease states such as atherosclerosis, inflammation or cancer. The ability to image MMP activity non-invasively in vivo, by radiolabelled synthetic inhibitors, would allow the characterization of atherosclerotic plaques, inflammatory lesions or tumors. Here we present an overview of radiolabelled MMP inhibitor...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010
Peng Fu Baozhong Shen Changjiu Zhao Guomei Tian

UNLABELLED The mouse double-minute 2 (MDM2) oncogene, amplified or overexpressed in many human cancers, has been suggested to be a novel target for cancer therapy. Visualization of MDM2 expression using radionuclide targeting can provide important diagnostic information in malignant tumors. The overall aim of this study was to evaluate whether liposome-coated (99m)Tc-radiolabeled antisense olig...

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