The excluded volume fraction for interstitial albumin (FE) was estimated in the lungs of seven mongrel dogs during steady state conditions following intravenous infusions of Ringer's solution, amounting to 0, 5, 10, and 15% of body weight (BW). We estimated the tissue blood volume with 51Cr red cells, extracellular space with 99mTc-diethylenetriaminepentaacetic acid (99mTc-DTPA), and the albumi...

Renal scintigraphy is a physio-functional exploration permitting the exploration and assertion of unilateral renal agenesis. We report the case of a patient followed for a right hydronephrosis having revealed an agenesis of the contralateral kidney confirmed by 99mTc-DMSA scintigraphy. Also 99mTc-DTPA scintigraphy allowed the evaluation of the permeability of the urinary tract of the single rig...

This study examined effects of three substances that cause mucosal provocation (histamine, ethanol, and the detergent dioctylsodium sulphosuccinate (DOSS] on the flux of solutes across airway vascular mucosal barriers in anaesthetised guinea pigs. The inward flux was assessed as absorption of iodine-131 labelled albumin (MW 69,000) from the tracheobronchial surface into the circulation and the ...

An index of pulmonary epithelial permeability has been studied in 12 patients with chronic renal failure during haemodialysis. It was assessed by the half time clearance from lung to blood (t 1/2 LB) of a nebulised solution containing technetium labelled diethylene triamine pentacetic acid (99mTc DTPA). Six patients were cigarette smokers and six were non-smokers. The non-smokers had greater pr...

tc-99m-ec is a new renal radiopharmaceutical introduced as an alternative for tc-99m mag3. twenty-three normal volunteers and patients in different .stages of renal disease were evaluated with te-99m ec and tc-99m dtpa. the mean initial uptake of ec was significantly higher as compared to dtpa. there was a high correlation between rectangular and hand-drawn rols for kidney and background, 0.96 ...

nuclear medicine methods have important role in the evaluation of transplanted kidney. in this study 58 99mtc-dtpa scans were performed in 38 patients. this method has 90% sensitivity and 96% specificity. in the cases of normal transplanted kidneys, function correlation between doppler sonography and scanning was more than dysfunctioning kidneys.

Angiotensin converting enzyme (ACE) inhibitor-induced renal failure has been reported in bilateral renal artery stenosis and in stenosis in solitary kidneys, but not in unilateral renal artery stenosis. In these patients, however, a functional impairment of the kidney ipsilateral to the stenosis can often be detected after ACE inhibition by scintigraphic techniques employing glomerular radionuc...

Aims and Objectives: Assessment of renal toxicity profile of 177Lu-DOTATATE based Peptide Receptor Radionuclide therapy (PRRT) in patients of Metastatic Neuroendocrine tumor (NET) with a single functioning kidney. Materials and Methods: This was a retrospective analysis of NET patients, who had undergone PRRT with 177Lu-DOTATATE at a large tertiary care centre. The patients selected for the stu...