In this paper we present an ontology-based data management (OBDM) project concerning the Italian public debt domain, carried out within a joint collaboration between Sapienza University of Rome and the Department of Treasury of the Italian Ministry of Economy and Finance. We discuss the motivations at the basis of this project and present the main characteristics of the ontology we have built. ...

We investigate the role of competition on the outcome of Austrian Treasury auctions. EU accession by Austria provides a “natural experiment” causing an exogenous increase in the number of bidders in Treasury Auctions. Difference-in-difference estimates suggest that the increased number in bidders caused a significant drop in the yields Austria had to pay for newly issued debt. We use structural...

in this paper, at first we reviewed the topics of literary modern criticism and psychological criticism and relationship between psychology and literature, paving the ground for the entry in the main topic. then we critique the modernist novel «when we left the bridge» by abdul rahman munif through archetypes put forward by psychologists and critics. in this paper criticism of the novel mention...

Drug-resistance acquisition through kinase gate-keeper mutations is a major hurdle in the clinic. Here, we determined the first crystal structures of the human FGFR4 kinase domain (FGFR4K) alone and complexed with ponatinib, a promiscuous type-2 (DFG-out) kinase inhibitor, and an oncogenic FGFR4K harboring the V550L gate-keeper mutation bound to FIIN-2, a new type-1 irreversible inhibitor. Rema...

We propose a theory of how the speech gesture determines change in a functionally relevant variable of vocal tract state (e.g., constriction degree). A core postulate of the theory is that the gesture determines how the variable evolves in time independently of any executive time-keeper. That is, the theory involves intrinsic timing of speech gestures. We compare the theory against others in wh...

It is a great pleasure to be here in Melbourne to deliver the Ian Little Memorial Lecture. I worked with Ian when we were both young recruits in the Research Department of the Reserve Bank in the early 1980s. I remember an easygoing young man with a cheerful disposition, and a mop of curly dark hair. Even then, Ian was a clear thinker with a strong commitment to good public policy. So it was no...

Clinical and research practices designed by developed countries are often implemented in host nations of the Third World. In recent years, a number of papers have presented a diversity of arguments to justify these practices which include the defence of research with placebos even though best proven treatments exist; the distribution of drugs unapproved in their country of origin; withholding o...