Journal of Policy Analysis and Management, Vol. 25, No. 3, 691–735 (2006) © 2006 by the Association for Public Policy Analysis and Management Published by Wiley Periodicals, Inc. Published online in Wiley InterScience (www.interscience.wiley.com) DOI: 10.1002/pam.20202 Submissions to Policy Retrospectives should be sent to Douglas J. Besharov, School of Public Policy, University of Maryland/Ame...

Signal recognition particle (SRP), an 11S ribonucleoprotein (Walter and Blobel (1982) Nature 299, 691-698), is required for translocation of secretory proteins across microsomal membranes (Walter and Blobel (1980) Proc. Natl. Acad. Sci. USA 77, 7112-7116) and for asymmetric integration into microsomal membranes of a transmembrane protein (Anderson et al., (1982) J. Cell Biol. 93, 501-506). We d...

A shifted cyclic reduction algorithm has been proposed by He, Meini, and Rhee [SIAM J. Matrix Anal. Appl., 23 (2001), pp. 673–691] for finding the stochastic matrix G associated with discrete-time quasi-birth-death (QBD) processes. We point out that the algorithm has quadratic convergence even for null recurrent QBDs. We also note that the approximations (to the matrix G) obtained by their algo...

2014 The use of magnetic fields in neutron scattering experimentation is reviewed briefly. Two general areas of application can be distinguished. In one the field acts to change the properties of the scattering sample ; in the second the field acts on the neutron itself. Several examples are discussed. Precautions necessary for high precision polarized beam measurements are reviewed. Revue Phys...

CASTELLANOS, A., JR & LEMBERG, L. (1966) Post-infarction conduction disturbances, Vectorcardiography-1965 (Ed. by I. Hoffman and R. C. Taymor), p. 219. North-Holland, Amsterdam. ROBERTSON, P.G.C., EMSLIE-SMITH, D., LOWE, K.G. & WATSON, H. (1963) The association of type B ventricular pre-excitation and right bundle-branch block. Brit. Heart J. 25, 755. SCOTT, R.C. (1965) Left bundle-branch block...

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,351 7.4 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,450 8.0 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,574 8.6 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,475 8.1 20 to 24 years . . . . . . . . . . . . . . . . ....

BACKGROUND Autosomal dominant non-autoimmune hyperthyroidism (ADNAH) is a rare genetic disorder of the endocrine system. Molecular genetic studies in ADNAH have revealed heterozygous germline mutations in the TSHR. To data, mutations leading to an increase in the constitutive activation of the TSHR have been described in the transmembrane segments, exoloops and cytoplasmic loop of TSHR. These m...

How large are the welfare e¤ects of EU enlargement and to what extent are skilled workers a¤ected di¤erently than unskilled workers in each region? In this paper, imperfect labor mobility is modeled within an economic geography framework to examine the welfare implications of goods and factor market integration. While unskilled workers are immobile, forward-looking skilled workers have the opti...

Mutations in the receptor tyrosine kinase FLT3 occur frequently in patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Small molecules that selectively inhibit FLT3 kinase activity induce apoptosis in blasts from AML patients with FLT3 mutations and prolong survival in animal models of FLT3-induced myeloproliferative disease. A spectrum of structurally different s...