Clinically useful antibiotics, β-lactams and vancomycin, are known to inhibit bacterial cell wall peptidoglycan synthesis. Methicillin-resistant Staphylococcus aureus (MRSA) has a unique cell wall structure consisting of peptidoglycan and wall teichoic acid. In recent years, new anti-infectious agents (spirohexaline, tripropeptin C, DMPI, CDFI, cyslabdan, 1835F03, and BPH-652) targeting MRSA ce...

The present study was carried out using seven parental lines including check CSV 46F and their 21 diallel crosses, excluding reciprocal. experiment evaluated in randomised block design with three replications during Kharif 2021 at the Centre for Millets Research, Sardarkrushinagar Dantiwada Agricultural University, Deesa. analysis of variance (mean sum squares) revealed significant differences ...

Appropriate addition of phosphate salt in food can improve the quality and taste. However, extensive intake may lead to some human diseases such as hyperphosphatemia renal insufficiency. Thus, it is essential establish a cost-effective, convenient, sensitive, selective method for monitoring ion (Pi) ensure control. In this work, Co-based metal-organic frameworks (Co-MOF) nanomaterial with dual ...

BACKGROUND Comparative genomic analysis of M. tuberculosis H37Rv and M. bovis BCG have shown that 16 RDs (Regions of Differences) are deleted in BCG and have shown six deletion regions in M. tuberculosis H37Rv. RD1, is present in M. tuberculosis but is absent in all M. bovis BCG sub-strains. A study from Kerala, a south-western coastal state of India aimed to find out differences in RD1 region ...

INTRODUCTION Breast cancer is a common disease with distinct tumor subtypes phenotypically characterized by ER and HER2/neu receptor status. MiRNAs play regulatory roles in tumor initiation and progression, and altered miRNA expression has been demonstrated in a variety of cancer states presenting the potential for exploitation as cancer biomarkers. Blood provides an excellent medium for biomar...

A limited number of reports have investigated the role of microRNAs in osteosarcoma. In this study, we performed miRNA expression profiling of osteosarcoma cell lines, tumor samples, and normal human osteoblasts. Twenty-two differentially expressed microRNAs were identified using high throughput real-time PCR analysis, and 4 (miR-135b, miR-150, miR-542-5p, and miR-652) were confirmed and valida...