Sebastian F. Mause1,2; Christian Weber1; José Sampol3; Francoise Dignat-George3 1Institute for Molecular Cardiovascular Research, Medical Faculty, RWTH Aachen University, Aachen, Germany; 2Department of Cardiology, Medical Faculty, RWTH Aachen University, Aachen, Germany; 3UMR-S 608 Inserm, Laboratoire d'hématologie et d'immunologie, UFR de pharmacie, Université de la Méditerranée, Marseille, F...

We present a high-resolution multiproxy middle Miocene sea surface temperature (SST) and productivity (SSP) reconstruction of Integrated Ocean Drilling Program Site U1318, from the upper slope edge (∼400 m water depth) Porcupine Basin continental margin, eastern North Atlantic Ocean. Biomarker dinoflagellate cyst proxies reveal warm mostly stratified waters during Climatic Optimum (MCO) that co...

MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...

MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...

MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...

MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...

MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...