s | 9 Purpose: We aimed to investigate the genetics of antidepressant response in patients with obsessive-compulsive disorder (OCD) in two ethnic groups. Hypothesis: We postulated that different genetic variations across known OCD candidate genes may predict antidepressant response in OCD patients with different ethnic background. Method: We examined two independent and ethnically different OCD...

BACKGROUND—Mental stress-induced myocardial ischemia (MSIMI) is common in patients with ischemic heart disease (IHD) and associated with a poorer cardiovascular prognosis. Platelet © 2014, Published by Mosby, Inc. This manuscript version is made available under the CC BY-NC-ND 4.0 license. Address for Correspondence: Wei Jiang, MD, Professor of Psychiatry & Behavioral Sciences, Professor of Med...

In a recent article, Blair (1) addresses the neurobiological mechanisms underlying psychopathic traits in childhood. The analysis conducted by the author provides a complete view about the complexity of neuro-functional factors underlying childhood psychopathy. In particular, the author focuses on the role played by structural, endocrinological, genetic, and environmental factors. Surprisingly,...

The report by Matthews et al 1 in this issue of Hypertension that increased systolic blood pressure reactivity while playing a video game predicts increased incidence of having some coronary calcification 13 years later is consistent with prior research they cite showing associations between cardiovascular reactivity to acute stress and various indices of atherosclerotic disease in human and an...

In a recent issue of Current Biology, Ventura and Worobey (2013) reviewed the literature about the variables which affect the development of food preferences across the lifespan. Among the numerous factors discussed by the authors the genetic influence seems to cover a key role. The review addressed this aspect by discussing the growing research about the genetic factors which are responsible o...

INTRODUCTION Why are some individuals more likely than others to develop a posttraumatic stress disorder (PTSD) in the face of similar levels of trauma exposure? Monitoring the traumatic process combining the antecedents, the determinants of the psychic trauma and the acute symptoms can clarify the causes of the final onset of a chronic repetition syndrome. Epidemiologic research has clarified ...