نتایج جستجو برای: 52 high week

تعداد نتایج: 2230247  

2016
Charles Peterfy Paul Emery Paul P Tak Mikkel Østergaard Julie DiCarlo Kati Otsa Federico Navarro Sarabia Karel Pavelka Marie-Agnes Bagnard Lykke Hinsch Gylvin Corrado Bernasconi Annarita Gabriele

OBJECTIVE To evaluate changes in structural damage and joint inflammation assessed by MRI following rituximab treatment in a Phase 3 study of patients with active rheumatoid arthritis (RA) despite methotrexate (MTX) who were naive to biological therapy. METHODS Patients were randomised to receive two infusions of placebo (n=63), rituximab 500 mg (n=62), or rituximab 1000 mg (n=60) intravenous...

2017
Richard A Furie Margaret Mitrane Enxu Zhao Patrice M Becker

Objective Post hoc analyses evaluated the effectiveness and safety of repository corticotropin injection (RCI) in patients with persistently active SLE over 52 weeks. Methods Patients were initially randomised to 40 U daily or 80 U every other day RCI (n=26) or placebo (n=12) for the 8-week double-blind period. Completers entered the open-label extension (OLE; n=33) receiving 16, 40 or 80 U R...

2014
S. R. Goldstein G. A. Bachmann P. R. Koninckx V. H. Lin D. J. Portman O. Ylikorkala

OBJECTIVE Assessment of 12-month safety of ospemifene 60 mg/day for treatment of postmenopausal women with vulvar and vaginal atrophy (VVA). METHODS In this 52-week, randomized, double-blind, placebo-controlled, parallel-group study, women 40-80 years with VVA and an intact uterus were randomized 6 : 1 to ospemifene 60 mg/day or placebo. The primary objective was 12-month safety, particularly...

2006
Susan James

National Vocational Qualifications (NVQs) were developed out of a plethora of initiatives implemented between 1960 and 1990. The format of NVQs was initially based on a hierarchical task analysis of job functions within the hospitality and catering industry, conducted as part of the CATERBASE project, which was commissioned by the Manpower Services Commission in the mid-1980s. This issues paper...

2014
J Sieper J Lenaerts J Wollenhaupt M Rudwaleit V I Mazurov L Myasoutova S Park Y Song R Yao D Chitkara N Vastesaeger

OBJECTIVE To investigate whether biologic-free remission can be achieved in patients with early, active axial spondyloarthritis (SpA) who were in partial remission after 28 weeks of infliximab (IFX)+naproxen (NPX) or placebo (PBO)+NPX treatment and whether treatment with NPX was superior to no treatment to maintain disease control. METHOD Infliximab as First-Line Therapy in Patients with Earl...

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