An efficient one-pot, three-component method for the preparation of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and various multi-substituted quinoline-3-carbonitrile derivatives has been developed through the Michael addition to enaminones, which was achieved by both microwave irradiation and conventional heating.

The evolution of heterocycles from hexaazaanthracene to tetraazapentacenes led to the discovery that syn aza-substituted polyazaacenes possess unusual zwitterionic structures. One of these, 5,7-diphenyl-5H,12H-quinoxalino[2,3-b]phenazine 4, first claimed in 1898 was fully characterized, including an X-ray crystal structure. These heteroacenes have a low calculated singlet-triplet gap and have u...

A new series of noncyclic ionophores containing two to four furan units (Ia to IIIb) i.e. 1,1-difurylethane (Ia), 2,5-bis(methylfurfuryl)furan (IIa) and 1,1’ ethyledenebis[5-(methylfurfuryl)furan] (IIIa), 2,2-difurylpropane (Ib), 2,5-bis (dimethylfurfuryl)furan(IIb), 2,2’-isopropylidenebis[5-(dimethylfurfuryl)furan] (IIIb) have been synthesized by the condensation of furan with acetaldehyde and...

The title compound, C21H29NO7 (1) [systematic name: benzyl ({(3aR,5S,6R,6aR)-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-di-methyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl}meth-yl)carbamate], consists of a substituted 2,2-di-methyl-tetra-hydro-furo[2,3-d][1,3]dioxolane skeleton. The furan-ose ring adopts an envelope conformation close to C 3-exo, where the C atom substituted by the benzyl carbamat...

Aromatic dicationic molecules possess impressive activity against a broad spectrum of microbial pathogens, including Pneumocystis carinii, Cryptosporidium parvum, and Candida albicans. In this work, 58 aromatic cations were examined for inhibitory activity against axenic amastigote-like Leishmania donovani parasites. In general, the most potent of the compounds were substituted diphenyl furan a...

The title compound, C13H21NO7 {systematic name: (3aR,5S,6R,6aR)-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-6-(nitro-meth-yl)tetra-hydro-furo[2,3-d][1,3]dioxole}, consists of a substituted 2,2-di-methyl-tetra-hydro-furo[2,3-d][1,3]dioxolane skeleton. The furan-ose ring A adopts a (o)T 4 conformation. The fused dioxolane ring B and the substituent dioxolane ring C also have twisted confo...